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Data for Sex- and gamete-specific patterns of X chromosome segregation in a trioecious nematode
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Pires da Silva, André (2017) Data for Sex- and gamete-specific patterns of X chromosome segregation in a trioecious nematode. [Dataset]
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Official URL: https://doi.org/10.17632/63d7rrrx28.3
Abstract
Three key steps in meiosis allow diploid organisms to produce haploid gametes: (1) homologous chromosomes (homologs) pair and undergo crossovers; (2) homologs segregate to opposite poles; and (3) sister chromatids segregate to opposite poles. The XX/XO sex determination system found in many nematodes [1] facilitates the study of meiosis because variation is easily recognized [2, 3, 4]. Here we show that meiotic segregation of X chromosomes in the trioecious nematode Auanema rhodensis [5] varies according to sex (hermaphrodite, female, or male) and type of gametogenesis (oogenesis or spermatogenesis). In this species, XO males exclusively produce X-bearing sperm [6, 7]. The unpaired X precociously separates into sister chromatids, which co-segregate with the autosome set to generate a functional haplo-X sperm. The other set of autosomes is discarded into a residual body. Here we explore the X chromosome behavior in female and hermaphrodite meioses. Whereas X chromosomes segregate following the canonical pattern during XX female oogenesis to yield haplo-X oocytes, during XX hermaphrodite oogenesis they segregate to the first polar body to yield nullo-X oocytes. Thus, crosses between XX hermaphrodites and males yield exclusively male progeny. During hermaphrodite spermatogenesis, the sister chromatids of the X chromosomes separate during meiosis I, and homologous X chromatids segregate to the functional sperm to create diplo-X sperm. Given these intra-species, intra-individual, and intra-gametogenesis variations in the meiotic program, A. rhodensis is an ideal model for studying the plasticity of meiosis and how it can be modulated.
| Item Type: | Dataset | ||||||||||||||||||
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| Subjects: | Q Science > QL Zoology | ||||||||||||||||||
| Divisions: | Faculty of Science > Life Sciences (2010- ) | ||||||||||||||||||
| Type of Data: | Experimental data | ||||||||||||||||||
| Library of Congress Subject Headings (LCSH): | Nematodes -- Reproduction, Nematodes -- Genetics, Intersexuality in animals, Meiosis, Gametes, Spermatogenesis, Chromosomes | ||||||||||||||||||
| Publisher: | Mendeley | ||||||||||||||||||
| Official Date: | 14 November 2017 | ||||||||||||||||||
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| Status: | Not Peer Reviewed | ||||||||||||||||||
| Publication Status: | Published | ||||||||||||||||||
| Media of Output: | .xlsx | ||||||||||||||||||
| Access rights to Published version: | Open Access | ||||||||||||||||||
| Copyright Holders: | University of Warwick | ||||||||||||||||||
| Description: | Data record consists of a single data file in .xlsx format. |
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