Skip to content Skip to navigation
University of Warwick
  • Study
  • |
  • Research
  • |
  • Business
  • |
  • Alumni
  • |
  • News
  • |
  • About

University of Warwick
Publications service & WRAP

Highlight your research

  • WRAP
    • Home
    • Search WRAP
    • Browse by Warwick Author
    • Browse WRAP by Year
    • Browse WRAP by Subject
    • Browse WRAP by Department
    • Browse WRAP by Funder
    • Browse Theses by Department
  • Publications Service
    • Home
    • Search Publications Service
    • Browse by Warwick Author
    • Browse Publications service by Year
    • Browse Publications service by Subject
    • Browse Publications service by Department
    • Browse Publications service by Funder
  • Help & Advice
University of Warwick

The Library

  • Login
  • Admin

The Personal Genome Project-UK, an open access resource of human multi-omics data

Tools
- Tools
+ Tools

Chervova, Olga, Conde, Lucia, Guerra-Assunção, José Afonso, Moghul, Ismail, Webster, Amy P., Berner, Alison, Larose Cadieux, Elizabeth, Tian, Yuan, Voloshin, Vitaly, Jesus, Tiago F., Hamoudi, Rifat, Herrero, Javier and Beck, Stephan (2019) The Personal Genome Project-UK, an open access resource of human multi-omics data. Scientific Data, 6 (1). 257. doi:10.1038/s41597-019-0205-4

[img]
Preview
PDF
WRAP-Personal-Genome-Project-UK-open-access-resource-human-multi-omics-data-Voloshin-2019.pdf - Published Version - Requires a PDF viewer.
Available under License Creative Commons Attribution 4.0.

Download (2202Kb) | Preview
Official URL: http://dx.doi.org/10.1038/s41597-019-0205-4

Request Changes to record.

Abstract

Integrative analysis of multi-omics data is a powerful approach for gaining functional insights into biological and medical processes. Conducting these multifaceted analyses on human samples is often complicated by the fact that the raw sequencing output is rarely available under open access. The Personal Genome Project UK (PGP-UK) is one of few resources that recruits its participants under open consent and makes the resulting multi-omics data freely and openly available. As part of this resource, we describe the PGP-UK multi-omics reference panel consisting of ten genomic, methylomic and transcriptomic data. Specifically, we outline the data processing, quality control and validation procedures which were implemented to ensure data integrity and exclude sample mix-ups. In addition, we provide a REST API to facilitate the download of the entire PGP-UK dataset. The data are also available from two cloud-based environments, providing platforms for free integrated analysis. In conclusion, the genotype-validated PGP-UK multi-omics human reference panel described here provides a valuable new open access resource for integrated analyses in support of personal and medical genomics.

Item Type: Journal Article
Subjects: Q Science > QH Natural history
Divisions: Faculty of Science > Engineering
Library of Congress Subject Headings (LCSH): Genomes , Human gene mapping, Gene mapping
Journal or Publication Title: Scientific Data
Publisher: Nature Publishing Group
ISSN: 2052-4463
Official Date: 31 October 2019
Dates:
DateEvent
31 October 2019Published
12 July 2019Accepted
Volume: 6
Number: 1
Article Number: 257
DOI: 10.1038/s41597-019-0205-4
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access
RIOXX Funder/Project Grant:
Project/Grant IDRIOXX Funder NameFunder ID
UNSPECIFIEDFrances and Augustus Newman Foundationhttp://dx.doi.org/10.13039/100007898
UNSPECIFIED Dangoor Educationhttp://dangooreducation.com/
BRC369/ CN/SB/101310[NIHR] National Institute for Health Researchhttp://dx.doi.org/10.13039/501100000272

Request changes or add full text files to a record

Repository staff actions (login required)

View Item View Item

Downloads

Downloads per month over past year

View more statistics

twitter

Email us: wrap@warwick.ac.uk
Contact Details
About Us