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Obesity : novel and unusual predisposing factors
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Hanson, Petra, Weickert, Martin O. and Barber, Thomas M. (2020) Obesity : novel and unusual predisposing factors. Therapeutic Advances in Endocrinology and Metabolism, 11 . pp. 1-14. doi:10.1177/2042018820922018 ISSN 2042-0188.
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WRAP-obesity-novel-unusual-predisposing-factors-Barber-2020.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons: Attribution-Noncommercial 4.0. Download (195Kb) | Preview |
Official URL: http://dx.doi.org/10.1177/2042018820922018
Abstract
To tackle the complexity of the global obesity epidemic, it is important to consider the many predisposing factors that underlie progressive and sustained weight gain. Some of the biological drivers for weight gain following initial weight loss include persistent changes in appetite hormones [including ghrelin and postprandial plasma peptide YY (PYY)], and ‘persistent metabolic adaptation’. However, many factors within our busy, stressful modern-day environment seem to conspire towards promotion of weight gain. These include the effects of sleep deprivation on appetite regulation, and the effects of modern-day technology on ‘attention competition’. These factors, combined with cultural and societal factors can result in a ‘mindless’ attitude regarding eating-related behaviour that is likely to predispose to weight gain. In addition to the external environment, our internal environment within the gut has also changed radically within the last few decades, resulting from changes in fibre intake, and increased ingestion of highly refined, sterilised and processed foods. Although contentious, these dietary changes have implications for our gut microbiota, and possible downstream effects on control of appetite and metabolism. In this brief review, we consider some of the novel predisposing factors for weight gain within our modern-day 21st century environments (both external and internal), and explore how legal terminology can help to conceptualise the numerous factors that contribute towards weight gain, and, ultimately the global obesity epidemic.
| Item Type: | Journal Article | ||||||||
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| Subjects: | G Geography. Anthropology. Recreation > GT Manners and customs R Medicine > RA Public aspects of medicine R Medicine > RB Pathology R Medicine > RC Internal medicine |
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| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Translational & Experimental Medicine > Metabolic and Vascular Health (- until July 2016) Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Translational & Experimental Medicine Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Library of Congress Subject Headings (LCSH): | Obesity, Metabolism -- Disorders , Obesity -- Psychological aspects, Food habits, Sleep deprivation , Endocrine disrupting chemicals , Post-traumatic stress disorder | ||||||||
| Journal or Publication Title: | Therapeutic Advances in Endocrinology and Metabolism | ||||||||
| Publisher: | Sage Publications Ltd | ||||||||
| ISSN: | 2042-0188 | ||||||||
| Official Date: | 1 January 2020 | ||||||||
| Dates: |
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| Volume: | 11 | ||||||||
| Page Range: | pp. 1-14 | ||||||||
| DOI: | 10.1177/2042018820922018 | ||||||||
| Status: | Peer Reviewed | ||||||||
| Publication Status: | Published | ||||||||
| Access rights to Published version: | Open Access (Creative Commons) | ||||||||
| Date of first compliant deposit: | 28 May 2020 | ||||||||
| Date of first compliant Open Access: | 28 May 2020 |
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