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Endovascular treatment versus medical therapy for hypertensive patients with renal artery stenosis : an updated systematic review

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Piaggio, Davide, Bracale, Umberto, Pecchia, Leandro, Di Taranto, Maria Donata, Sodo, Maurizio and Bracale, Umberto Marcello (2019) Endovascular treatment versus medical therapy for hypertensive patients with renal artery stenosis : an updated systematic review. Annals of Vascular Surgery, 61 . pp. 445-454. doi:10.1016/j.avsg.2019.04.050

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Official URL: https://doi.org/10.1016/j.avsg.2019.04.050

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Abstract

The benefit of balloon angioplasty, with or without stenting, for the treatment of patients with renal artery stenosis remains controversial. A number of randomized controlled trials have attempted to determine its efficacy but the matter remains unclear. A 2014 Cochrane review, which combined data from 8 trials, showed homogeneity among the trials with no significant benefit shown. This systematic review replicates the same research methods and meta-analysis while expanding it to include papers between 2014 and 2018. One of the trials included in the previous review published results in the interim. Additionally, 2 ongoing trials identified in the 2014 review are yet to publish any result. Meta-analysis of the reports showed no heterogeneity between trials and no significant improvement shown by balloon angioplasty, with or without stenting, versus medical therapy. Further studies are recommended in order to assess the benefits of balloon angioplasty for patients with more severe renal artery stenosis.

Item Type: Journal Article
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Science > Engineering
Journal or Publication Title: Annals of Vascular Surgery
Publisher: Elsevier
ISSN: 0890-5096
Official Date: 1 November 2019
Dates:
DateEvent
1 November 2019Published
31 July 2019Available
27 April 2019Accepted
Volume: 61
Page Range: pp. 445-454
DOI: 10.1016/j.avsg.2019.04.050
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access

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