Recent developments in the area of asymmetric transfer hydrogenation
UNSPECIFIED. (2000) Recent developments in the area of asymmetric transfer hydrogenation. MOLECULES, 5 (1). pp. 4-18. ISSN 1420-3049Full text not available from this repository.
The use of an enantiomerically pure amino alcohol, coupled to a transfer hydrogenation process, in the asymmetric catalysis of the reduction of ketones to alcohols, is described. The process works well for unfunctionalised ketones, affording e.e.s of up to 98%, and excellent conversions. We have recently extended, for the first time in this application, the scope of the methodology to the reductions of alpha-heteroatom substituted substrates, through the use of the appropriate protecting groups on each atom.
|Item Type:||Journal Article|
|Subjects:||Q Science > QD Chemistry|
|Journal or Publication Title:||MOLECULES|
|Publisher:||MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL|
|Number of Pages:||15|
|Page Range:||pp. 4-18|
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