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Covid-19 and cardiovascular risk : susceptibility to infection to SARS-CoV-2, severity and prognosis of Covid-19 and blockade of the renin-angiotensin-aldosterone system. An evidence-based viewpoint

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Cappuccio, Francesco and Siani, Alfonso (2020) Covid-19 and cardiovascular risk : susceptibility to infection to SARS-CoV-2, severity and prognosis of Covid-19 and blockade of the renin-angiotensin-aldosterone system. An evidence-based viewpoint. Nutrition, Metabolism and Cardiovascular Diseases, 30 (8). pp. 1227-1235. doi:10.1016/j.numecd.2020.05.013

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WRAP-Covid-19-cardiovascular-risk-infection-viewpoint-Cappuccio-2020.pdf - Accepted Version
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Official URL: https://doi.org/10.1016/j.numecd.2020.05.013

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Abstract

The presence of cardiovascular co-morbidities and the known effects of coronaviruses on the cardiovascular system have called attention to the potential implications for patients with cardiovascular risk factors. This evidence-based viewpoint will address two questions: (a) are individuals with underlying cardiovascular risk factors (e.g. high blood pressure or diabetes) or overt disease (e.g. coronary heart disease, heart failure, kidney disease) more likely to develop severe Covid-19 and to die than those without underlying conditions? (b) does the regular use of angiotensin-converting enzyme inhibitors (ACE-i) or angiotensin-receptor blockers (ARB) make patients more likely to get infected and to die of Covid-19?

Item Type: Journal Article
Alternative Title: Nutrition Metabolism and Cardiovascular Disease 2020; 30: 1227 - 1235
Subjects: Q Science > QP Physiology
Q Science > QR Microbiology
R Medicine > RA Public aspects of medicine
R Medicine > RC Internal medicine
Divisions: Faculty of Medicine > Warwick Medical School > Health Sciences
Faculty of Medicine > Warwick Medical School > Health Sciences > Mental Health and Wellbeing
Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): COVID-19 (Disease), Coronavirus infections, Coronaviruses, SARS (Disease), Hypertension, Diabetes -- Complications, Cardiovascular system -- Diseases, Angiotensin converting enzyme -- Inhibitors, Angiotensins, Renin-angiotensin system
Journal or Publication Title: Nutrition, Metabolism and Cardiovascular Diseases
Publisher: Elsevier Ltd
ISSN: 0939-4753
Official Date: 24 July 2020
Dates:
DateEvent
24 July 2020Published
28 May 2020Available
18 May 2020Accepted
Date of first compliant deposit: 2 June 2020
Volume: 30
Number: 8
Page Range: pp. 1227-1235
DOI: 10.1016/j.numecd.2020.05.013
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access
Copyright Holders: © 2020 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved
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