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Partial scanning transmission electron microscopy with deep learning

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Ede, Jeffrey M. and Beanland, Richard (2020) Partial scanning transmission electron microscopy with deep learning. Scientific Reports, 10 . 8332. doi:10.1038/s41598-020-65261-0 ISSN 2045-2322.

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Official URL: http://dx.doi.org/10.1038/s41598-020-65261-0

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Abstract

Compressed sensing algorithms are used to decrease electron microscope scan time and electron beam exposure with minimal information loss. Following successful applications of deep learning to compressed sensing, we have developed a two-stage multiscale generative adversarial neural network to complete realistic 512 × 512 scanning transmission electron micrographs from spiral, jittered gridlike, and other partial scans. For spiral scans and mean squared error based pre-training, this enables electron beam coverage to be decreased by 17.9× with a 3.8% test set root mean squared intensity error, and by 87.0× with a 6.2% error. Our generator networks are trained on partial scans created from a new dataset of 16227 scanning transmission electron micrographs. High performance is achieved with adaptive learning rate clipping of loss spikes and an auxiliary trainer network. Our source code, new dataset, and pre-trained models are publicly available.

Item Type: Journal Article
Subjects: Q Science > QA Mathematics > QA76 Electronic computers. Computer science. Computer software
Q Science > QC Physics
Q Science > QH Natural history
Divisions: Faculty of Science, Engineering and Medicine > Science > Physics
Library of Congress Subject Headings (LCSH): Scanning transmission electron microscopy , Machine learning
Journal or Publication Title: Scientific Reports
Publisher: Nature Publishing Group
ISSN: 2045-2322
Official Date: 20 May 2020
Dates:
DateEvent
20 May 2020Published
28 April 2020Accepted
Volume: 10
Article Number: 8332
DOI: 10.1038/s41598-020-65261-0
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access (Creative Commons)
Date of first compliant deposit: 1 July 2020
Date of first compliant Open Access: 2 July 2020
RIOXX Funder/Project Grant:
Project/Grant IDRIOXX Funder NameFunder ID
EP/N035437/1[EPSRC] Engineering and Physical Sciences Research Councilhttp://dx.doi.org/10.13039/501100000266
1917382[EPSRC] Engineering and Physical Sciences Research Councilhttp://dx.doi.org/10.13039/501100000266

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