Novel catalysts for asymmetric reduction of carbonyl groups
UNSPECIFIED (1999) Novel catalysts for asymmetric reduction of carbonyl groups. In: 9th International Symposium on the Relations between Homogeneous and Heterogeneous Catalysis (SHHC-9), UNIV SOUTHAMPTON, SOUTHAMPTON, ENGLAND, JUL 19-24, 1998. Published in: JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 146 (1-2). pp. 139-148.Full text not available from this repository.
The use of (i) enantiomerically pure phosphinamides coupled to borane and (ii) an enantiomerically pure amino alcohol coupled to a transfer hydrogenation process, in the asymmetric catalysis of the reduction of ketones to alcohols, is described. The former process is particularly suited to the reduction of alpha-chlorinated substrates, affording e.e.s of up to 94%, whilst the latter process is optimal for unfunctionalised ketones, affording e.e.s of up to 98%. (C) 1999 Elsevier Science B.V. All rights reserved.
|Item Type:||Conference Item (UNSPECIFIED)|
|Subjects:||Q Science > QD Chemistry|
|Journal or Publication Title:||JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL|
|Publisher:||ELSEVIER SCIENCE BV|
|Date:||20 October 1999|
|Number of Pages:||10|
|Page Range:||pp. 139-148|
|Title of Event:||9th International Symposium on the Relations between Homogeneous and Heterogeneous Catalysis (SHHC-9)|
|Location of Event:||UNIV SOUTHAMPTON, SOUTHAMPTON, ENGLAND|
|Date(s) of Event:||JUL 19-24, 1998|
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