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Nuclear events during infection of avian fibroblasts with influenza virus

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Stephenson, John Robert (1975) Nuclear events during infection of avian fibroblasts with influenza virus. PhD thesis, University of Warwick.

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Official URL: http://webcat.warwick.ac.uk/record=b1747721~S15

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Abstract

The work presented in this thesis is an attempt to evaluate the Molecular mechanisms of both host and viral nucleic acid metabolism in the nucleus of avian fibroblasts infected with influenza virus.

The first section describes the alteration of the processing of rRNA in the nucleus of virus infected cells.

The second section describes the kinetics of virus adsorption at 4° and room temperature and the occurrence of micropinocytosis in CEF cells at 4°.

The third section describes the movement of viral nucleic acid into the nucleus of infected cells, its association with the cellular DNA and the subsequent exit of the viral RNA from the nucleus.

Item Type: Thesis or Dissertation (PhD)
Subjects: Q Science > QH Natural history
Q Science > QL Zoology
Q Science > QP Physiology
R Medicine > RA Public aspects of medicine
Library of Congress Subject Headings (LCSH): Molecular biology -- Research, Ornithology, Influenza, Fibroblasts, RNA, Adsorption (Biology)
Official Date: February 1975
Dates:
DateEvent
February 1975Submitted
Institution: University of Warwick
Theses Department: Department of Biological Sciences
Thesis Type: PhD
Publication Status: Unpublished
Supervisor(s)/Advisor: Dimmock, N. J.
Sponsors: Cancer Research Campaign (Great Britain)
Extent: 192 leaves : illustrations, charts
Language: eng

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