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Matrix protein of chandipura virus inhibits transcription from an RNA polymerase II promoter
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UNSPECIFIED (1999) Matrix protein of chandipura virus inhibits transcription from an RNA polymerase II promoter. VIRUS GENES, 19 (3). pp. 223-228. ISSN 0920-8569.
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Abstract
Chandipura virus (CHPV) is a Vesiculovirus, related to, but phylogenetically distinct from, vesicular stomatitis virus (VSV). The matrix protein of VSV, as well as its role in virus assembly, inhibits the transcription from promoters for host RNA polymerases I and II. Cloning and expression of the matrix protein of CHPV in human cells showed that this protein is also functional in its inhibitory effect on transcription of a reporter gene from the cytomegalovirus immediate-early promoter, despite sharing only 28% amino acid sequence identity with the matrix protein of VSV.
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Subjects: | Q Science > QH Natural history > QH426 Genetics Q Science > QR Microbiology > QR355 Virology |
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| Journal or Publication Title: | VIRUS GENES | ||||
| Publisher: | KLUWER ACADEMIC PUBL | ||||
| ISSN: | 0920-8569 | ||||
| Official Date: | November 1999 | ||||
| Dates: |
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| Volume: | 19 | ||||
| Number: | 3 | ||||
| Number of Pages: | 6 | ||||
| Page Range: | pp. 223-228 | ||||
| Publication Status: | Published |
Data sourced from Thomson Reuters' Web of Knowledge
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