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Matrix protein of chandipura virus inhibits transcription from an RNA polymerase II promoter

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UNSPECIFIED (1999) Matrix protein of chandipura virus inhibits transcription from an RNA polymerase II promoter. VIRUS GENES, 19 (3). pp. 223-228. ISSN 0920-8569.

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Abstract

Chandipura virus (CHPV) is a Vesiculovirus, related to, but phylogenetically distinct from, vesicular stomatitis virus (VSV). The matrix protein of VSV, as well as its role in virus assembly, inhibits the transcription from promoters for host RNA polymerases I and II. Cloning and expression of the matrix protein of CHPV in human cells showed that this protein is also functional in its inhibitory effect on transcription of a reporter gene from the cytomegalovirus immediate-early promoter, despite sharing only 28% amino acid sequence identity with the matrix protein of VSV.

Item Type: Journal Article
Subjects: Q Science > QH Natural history > QH426 Genetics
Q Science > QR Microbiology > QR355 Virology
Journal or Publication Title: VIRUS GENES
Publisher: KLUWER ACADEMIC PUBL
ISSN: 0920-8569
Official Date: November 1999
Dates:
DateEvent
November 1999UNSPECIFIED
Volume: 19
Number: 3
Number of Pages: 6
Page Range: pp. 223-228
Publication Status: Published

Data sourced from Thomson Reuters' Web of Knowledge

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