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P-COSCA (Pediatric Core Outcome Set for Cardiac Arrest) in children : an advisory statement from the International Liaison Committee on Resuscitation
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Topijian, Alexis, Scholefield, Barnaby, Pinto, Neethi, Fink, Ericka, Buysse, Corinne, Haywood, Kirstie L., Maconochie, Ian, Nadkarni, Vinay, de Caen, Allan, Escalante-Kanashiro, Raffo, Ng, Kee-Chong, Nuthall, Gabrielle, Reis, Amelia, Van de Voorde, Patrick, Suskauer, Stacy, Schexnayder, Steven, Hazinski, Mary Fran and Slomine, Beth (2021) P-COSCA (Pediatric Core Outcome Set for Cardiac Arrest) in children : an advisory statement from the International Liaison Committee on Resuscitation. Circulation, 142 (16). e246-e261. doi:10.1161/CIR.0000000000000911 ISSN 0009-7322.
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WRAP-P-COSCA-(Pediatric-Core-Outcome-Set-Cardiac-Arrest)-children-Haywood-2020.pdf - Accepted Version - Requires a PDF viewer. Download (977Kb) | Preview |
Official URL: https://doi.org/10.1161/CIR.0000000000000911
Abstract
Studies of pediatric cardiac arrest use inconsistent outcomes, including return of spontaneous circulation and short-term survival, and basic assessments of functional and neurological status. In 2018, the International Liaison Committee on Resuscitation sponsored the COSCA initiative (Core Outcome Set After Cardiac Arrest) to improve consistency in reported outcomes of clinical trials of adult cardiac arrest survivors and supported this P-COSCA initiative (pediatric COSCA). The P-COSCA Steering Committee generated a list of potential survival, life impact, and economic impact outcomes and assessment time points that were prioritized by a multidisciplinary group of healthcare providers, researchers, and parents/caregivers of children who survived cardiac arrest. Then, expert panel discussions achieved consensus regarding the core outcomes, the methods to measure those core outcomes, and the timing of the measurements. The P-COSCA includes assessment of survival, brain function, cognitive function, physical function, and basic daily life skills. Survival and brain function were assessed at discharge or 30 days (or both if possible) and between 6 and 12 months postarrest. Cognitive function, physical function, and basic daily life skills were assessed between 6 and 12 months after cardiac arrest. Because many children have prearrest comorbidities, the P-COSCA also includes documentation of baseline (ie, prearrest) brain function and calculation of changes after cardiac arrest. Supplementary outcomes of survival, brain function, cognitive function, physical function, and basic daily life skills are assessed at 3 months and beyond 1 year after cardiac arrest if resources are available.
Item Type: | Journal Article | ||||||||
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Subjects: | R Medicine > RJ Pediatrics | ||||||||
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Warwick Research in Nursing |
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Library of Congress Subject Headings (LCSH): | Cardiac arrest in children, Pediatric cardiology, Pediatric anesthesia, Heart failure, Cardiac resuscitation, Cardiovascular emergencies | ||||||||
Journal or Publication Title: | Circulation | ||||||||
Publisher: | American Heart Association | ||||||||
ISSN: | 0009-7322 | ||||||||
Official Date: | 12 July 2021 | ||||||||
Dates: |
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Volume: | 142 | ||||||||
Number: | 16 | ||||||||
Page Range: | e246-e261 | ||||||||
DOI: | 10.1161/CIR.0000000000000911 | ||||||||
Status: | Peer Reviewed | ||||||||
Publication Status: | Published | ||||||||
Access rights to Published version: | Restricted or Subscription Access | ||||||||
Copyright Holders: | © 2020 American Heart Association, Inc. | ||||||||
Description: | Free access |
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Date of first compliant deposit: | 3 September 2020 | ||||||||
Date of first compliant Open Access: | 24 March 2021 | ||||||||
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