Hydrogen bond template-directed polymerization of protected 5 '-acryloylnucleosides
UNSPECIFIED. (1999) Hydrogen bond template-directed polymerization of protected 5 '-acryloylnucleosides. MACROMOLECULES, 32 (20). pp. 6560-6564. ISSN 0024-9297Full text not available from this repository.
Poly(5'-acryloyluridine) has been shown to act as a template in the radical polymerization of the complementary 5'-acryloyladenosine in the presence of the noncomplementary 5'-acryloyluridine. The template was synthesized by polymerizing 5'-acryloyluridine using AIBN as the initiator. The 5'-acryloylnucleosides were synthesized by regiospecific acylation of adenosine and uridine at the 5'-position using the enzyme Candida antarctica lipase 435 (CAL 435). The remaining hydroxyl groups were protected as silyl ethers to increase the solubility in nonpolar solvents.
|Item Type:||Journal Article|
|Subjects:||Q Science > QD Chemistry|
|Journal or Publication Title:||MACROMOLECULES|
|Publisher:||AMER CHEMICAL SOC|
|Official Date:||5 October 1999|
|Number of Pages:||5|
|Page Range:||pp. 6560-6564|
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