Glycosidase-catalysed synthesis of alpha-galactosyl epitopes important in xenotransplantation and toxin binding using the alpha-galactosidase from Penicillium multicolor
UNSPECIFIED. (1999) Glycosidase-catalysed synthesis of alpha-galactosyl epitopes important in xenotransplantation and toxin binding using the alpha-galactosidase from Penicillium multicolor. CHEMICAL COMMUNICATIONS (20). pp. 2065-2066. ISSN 1359-7345Full text not available from this repository.
The alpha-galactosidase from Penicillium multicolor catalyses highly regioselective galactosyl transfer on to mono- and di-saccharide acceptors that have a non-reducing terminal galactose unit to give products containing the alpha-D-Galp-(1 --> 3)-D-Galp epitope found on pig tissue and which is responsible for the hyperacute rejection response in xenotransplantation of pig organs into man.
|Item Type:||Journal Article|
|Subjects:||Q Science > QD Chemistry|
|Journal or Publication Title:||CHEMICAL COMMUNICATIONS|
|Publisher:||ROYAL SOC CHEMISTRY|
|Official Date:||21 October 1999|
|Number of Pages:||2|
|Page Range:||pp. 2065-2066|
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