Bell, Colette, Muhammad, Abdul Hadi, Khanal, Saval and Paudyal, Vibhu (2021) Prescribing patterns and costs associated with erectile dysfunction drugs in England : a time trend analysis. BJGP Open, 5 (2). bjgpopen20X101145. doi:10.3399/bjgpopen20X101145 ISSN 2398-3795.

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Abstract

Background Sildenafil and tadalafil are recommended firstline treatments for erectile dysfunction (ED). Sildenafil was legally reclassified to a ‘pharmacy’ medicine in the UK in 2018.

Aim To assess the prescribing patterns and costs associated with prescribing of ED drugs in England, and to investigate the link between prescribing and deprivation, regional demography, and legal reclassification.

Design & setting Analyses were conducted of publicly available government data from various sources pertaining to primary care prescribing and demographics in England.

Method Prescribing and cost data from January 2009 to November 2019 were extracted and adjusted for inflation, male populations, and regional deprivation.

Results Between 2009 and 2019 the rate of prescribing, measured as the number of items per 1000 men, increased by 110%. In 2019, the rate of prescribing of ED medicines in the most deprived areas was 21.0% higher than the rate observed in least deprived areas. The northern regions of England approximately had a 50% higher rate of prescribing compared with London. A 1.3% annual increase in the number of prescription items was observed between 2018 and 2019 for Sildenafil, with a 5.8% increase observed from 2017–2018.

Conclusion The two-fold increase in the rate of primary care prescriptions in the past 10 years suggests that more men are being screened for, or seeking help for, ED. The higher rate of prescribing offers opportunity for monitoring of linked risk factors, such as diabetes mellitus, dyslipidaemia, and vascular disorders, in deprived populations. Reclassification of sildenafil had a modest impact on prescribing practices.

Item Type:	Journal Article
Subjects:	R Medicine > RC Internal medicine
Divisions:	Faculty of Social Sciences > Warwick Business School > Behavioural Science Faculty of Social Sciences > Warwick Business School
Library of Congress Subject Headings (LCSH):	Impotence, Infertility, Male, Infertility, Male -- Treatment, Infertility, Male -- Treatment -- Cost effectiveness, Sildenafil -- Cost effectiveness
Journal or Publication Title:	BJGP Open
Publisher:	Royal College of General Practitioners
ISSN:	2398-3795
Official Date:	2 February 2021
Dates:	Date Event 2 February 2021 Published 8 December 2020 Available 7 July 2020 Accepted
Volume:	5
Number:	2
Article Number:	bjgpopen20X101145
DOI:	10.3399/bjgpopen20X101145
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Open Access (Creative Commons)
Date of first compliant deposit:	15 December 2020
Date of first compliant Open Access:	16 December 2020
RIOXX Funder/Project Grant:	Project/Grant ID RIOXX Funder Name Funder ID UNSPECIFIED University Of Birmingham http://dx.doi.org/10.13039/501100000855

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