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Stereoselectivity in amidyl radical cyclisations: Alkyl mode cyclisations

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UNSPECIFIED (1999) Stereoselectivity in amidyl radical cyclisations: Alkyl mode cyclisations. SYNLETT (4). pp. 444-446. ISSN 0936-5214

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Abstract

Amidyl radicals 2 generated from tributylstannane mediated homolysis of O-benzoyl hydroxamic acid derivatives 6a-g undergo alkyl mode 5-exo cyclisation to give mixtures of cis and trans N-acyl pyrrolidinones (d.e. = 54-74%). The efficiency of the process was found to be dependant upon the steric and electronic nature of the nitrogen substituent.

Item Type: Journal Article
Subjects: Q Science > QD Chemistry
Journal or Publication Title: SYNLETT
Publisher: GEORG THIEME VERLAG
ISSN: 0936-5214
Date: April 1999
Number: 4
Number of Pages: 3
Page Range: pp. 444-446
Publication Status: Published
URI: http://wrap.warwick.ac.uk/id/eprint/14587

Data sourced from Thomson Reuters' Web of Knowledge

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