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Temporal development of Drosophila embryos is highly robust across a wide temperature range
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Chong, Jeronica, Amourda, Christopher and Saunders, Timothy E. (2018) Temporal development of Drosophila embryos is highly robust across a wide temperature range. Journal of The Royal Society Interface, 15 (144). 20180304. doi:10.1098/rsif.2018.0304
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Official URL: http://dx.doi.org/10.1098/rsif.2018.0304
Abstract
Development is a process precisely coordinated in both space and time. Spatial precision has been quantified in a number of developmental systems, and such data have contributed significantly to our understanding of, for example, morphogen gradient interpretation. However, comparatively little quantitative analysis has been performed on timing and temporal coordination during development. Here, we use Drosophila to explore the temporal robustness of embryonic development within physiologically normal temperatures. We find that development is temporally very precise across a wide range of temperatures in the three Drosophila species investigated. However, we find temperature dependence in the timing of developmental events. A simple model incorporating history dependence can explain the developmental temporal trajectories. Interestingly, history dependence is temperature-specific, with either effective negative or positive feedback at different temperatures. We also find that embryos are surprisingly robust to shifting temperatures during embryogenesis. We further identify differences between tropical and temperate species, potentially due to different mechanisms regulating temporal development that depend on the local environment. Our data show that Drosophila embryonic development is temporally robust across a wide range of temperatures. This robustness shows interesting species-specific differences that are suggestive of different sensitivity to temperature fluctuations between Drosophila species.
| Item Type: | Journal Article | ||||||
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| Subjects: | Q Science > QH Natural history Q Science > QL Zoology Q Science > QP Physiology |
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| Divisions: | Faculty of Medicine > Warwick Medical School > Biomedical Sciences Faculty of Medicine > Warwick Medical School |
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| Library of Congress Subject Headings (LCSH): | Drosophila, Embryology, Developmental biology, Temperature -- Physiological effect | ||||||
| Journal or Publication Title: | Journal of The Royal Society Interface | ||||||
| Publisher: | The Royal Society Publishing | ||||||
| ISSN: | 1742-5689 | ||||||
| Official Date: | 11 July 2018 | ||||||
| Dates: |
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| Date of first compliant deposit: | 13 January 2021 | ||||||
| Volume: | 15 | ||||||
| Number: | 144 | ||||||
| Article Number: | 20180304 | ||||||
| DOI: | 10.1098/rsif.2018.0304 | ||||||
| Status: | Peer Reviewed | ||||||
| Publication Status: | Published | ||||||
| Access rights to Published version: | Open Access | ||||||
| RIOXX Funder/Project Grant: |
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