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Improved social functioning following social recovery therapy in first episode psychosis : do social cognition and neurocognition improve following therapy, and do they predict treatment response?

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Lowri Griffiths, Siân, Wood, Stephen J., Fowler, David, Freemantle, Nick, Hodgekins, Joanne, Singh, Swaran P., Sharma, Vimal, Birchwood, Max and Jones, Peter B. (2021) Improved social functioning following social recovery therapy in first episode psychosis : do social cognition and neurocognition improve following therapy, and do they predict treatment response? Schizophrenia Research, 228 . pp. 249-255. doi:10.1016/j.schres.2020.12.023 ISSN 0920-9964.

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Official URL: https://doi.org/10.1016/j.schres.2020.12.023

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Abstract

There is a need to develop and refine psychosocial interventions to improve functioning in First Episode Psychosis (FEP). Social cognition and neurocognition are closely linked to functioning in psychosis; examinations of cognition pre- and post- psychosocial intervention may provide insights into the mechanisms of these interventions, and identify which individuals are most likely to benefit.

Method:
Cognition was assessed within a multi-site trial of Social Recovery Therapy (SRT) for individuals with FEP experiencing poor functioning (<30 h weekly structured activity). Fifty-nine participants were randomly allocated to the therapy group (SRT + Early intervention), and 64 were allocated to treatment as usual group (TAU - early intervention care). Social cognition and neurocognition were assessed at baseline and 9 months; assessors were blind to group allocation. It was hypothesized that social cognition would improve following therapy, and those with better social cognition prior to therapy would benefit the most from SRT.

Results:
There was no significant impact of SRT on individual neurocognitive or social cognitive variables, however, joint models addressing patterns of missingness demonstrate improvement across a number of cognitive outcomes following SRT. Further, regression analyses showed those who had better social cognition at baseline were most likely to benefit from the therapy (ß = 0.350; 95% CI = 0.830 to 8.891; p = .019).

Conclusion:
It is not clear if SRT impacts on social cognitive or neurocognitive function, however, SRT may be beneficial in those with better social cognition at baseline.

Item Type: Journal Article
Subjects: B Philosophy. Psychology. Religion > BF Psychology
R Medicine > RC Internal medicine
Divisions: Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Dean's Office & Professional Support Services
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Mental Health and Wellbeing
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Psychoses -- Diagnosis -- Treatment, Cognitive therapy, Evidence-based psychotherapy, Cognitive psychology
Journal or Publication Title: Schizophrenia Research
Publisher: Elsevier BV
ISSN: 0920-9964
Official Date: February 2021
Dates:
DateEvent
February 2021Published
22 January 2021Available
29 December 2020Accepted
Volume: 228
Page Range: pp. 249-255
DOI: 10.1016/j.schres.2020.12.023
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
Date of first compliant deposit: 14 January 2021
Date of first compliant Open Access: 22 January 2022
RIOXX Funder/Project Grant:
Project/Grant IDRIOXX Funder NameFunder ID
RP-PG-0109-10 074[NIHR] National Institute for Health Researchhttp://dx.doi.org/10.13039/501100000272
ARC-WM[NIHR] National Institute for Health Researchhttp://dx.doi.org/10.13039/501100000272
ARC East of England[NIHR] National Institute for Health Researchhttp://dx.doi.org/10.13039/501100000272
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