Selective and reversible reduction of odor sensitivity in the rat by concanavalin A
UNSPECIFIED. (1998) Selective and reversible reduction of odor sensitivity in the rat by concanavalin A. PHYSIOLOGY & BEHAVIOR, 65 (3). pp. 513-516. ISSN 0031-9384Full text not available from this repository.
Rats were trained using an olfactometer to detect low concentrations of ethyl acetate (EA) or dimethyl disulphide vapor (DMDS). Concanavalin A (ConA) applied to the olfactory mucosa had no effect on ability of rats to detect low concentrations of EA but produced a marked deficit in detection in DMDS. DMDS detection performance returned to control levels 3 days after the ConA treatment. These results provide the first behavioral evidence for odor-specific inhibition by chemical modification of the olfactory epithelium and support the notion that ConA selectively inactivates one or more types (subclasses) of olfactory receptor proteins. (C) 1998 Elsevier Science Inc.
|Item Type:||Journal Article|
|Subjects:||B Philosophy. Psychology. Religion > BF Psychology|
|Journal or Publication Title:||PHYSIOLOGY & BEHAVIOR|
|Publisher:||PERGAMON-ELSEVIER SCIENCE LTD|
|Date:||1 December 1998|
|Number of Pages:||4|
|Page Range:||pp. 513-516|
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