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The association between exposure to domestic abuse in women and the development of syndromes indicating central nervous system sensitization : a retrospective cohort study using UK primary care records
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Chandan, Joht Singh, Keerthy, Deepiksana, Gokhale, Krishna Margadhamane, Bradbury‐Jones, Caroline, Raza, Karim, Bandyopadhyay, Siddhartha, Taylor, Julie and Nirantharakumar, Krishnarajah (2021) The association between exposure to domestic abuse in women and the development of syndromes indicating central nervous system sensitization : a retrospective cohort study using UK primary care records. European Journal of Pain, 25 (6). pp. 1283-1291. doi:10.1002/ejp.1750 ISSN 1090-3801.
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Official URL: http://dx.doi.org/10.1002/ejp.1750
Abstract
Background:
Domestic abuse is a global public health issue. The association between the development of central sensitivity syndromes (CSS) and previous exposure to domestic abuse has been poorly understood particularly within European populations.
Methods:
A retrospective cohort study using the ‘The Health Improvement Network,’ (UK primary care medical records) between 1st January 1995–31st December 2018. 22,604 adult women exposed to domestic abuse were age matched to 44,671 unexposed women. The average age at cohort entry was 36 years and the median follow-up was 2.5 years. The outcomes of interest were the development of a variety of syndromes which demonstrate central nervous system sensitization. Fibromyalgia, chronic fatigue syndrome and temporomandibular joint disorder outcomes have been reported previously. Outcomes were adjusted for the presence of mental ill health.
Results:
During the study period, women exposed to domestic abuse experienced an increased risk of developing chronic lower back pain (adjusted incidence rate ratio [aIRR] 2.28; 95% CI 1.85–2.80), chronic headaches (aIRR 3.15; 95% CI 1.07–9.23), irritable bowel syndrome (aIRR 1.41; 95% CI 1.25–1.60) and restless legs syndrome (aIRR 1.89; 95% CI 1.44–2.48). However, no positive association was seen with the development of interstitial cystitis (aIRR 0.52; 95% CI 0.14–1.93), vulvodynia (aIRR 0.42; 95% CI 0.14–1.25) and myofascial pain syndrome (aIRR 1.01; 95% CI 0.28–3.61).
Conclusion:
This study demonstrates the need to consider a past history of domestic abuse in patients presenting with CSS; and also consider preventative approaches in mitigating the risk of developing CSS following exposure to domestic abuse.
Significance:
Domestic abuse is a global public health issue, with a poorly understood relationship with the development of complex pain syndromes. Using a large UK primary care database, we were able to conduct the first global cohort study to explore this further. We found a strong pain morbidity burden associated with domestic abuse, suggesting the need for urgent public health intervention to not only prevent domestic abuse but also the associated negative pain consequences.
Item Type: | Journal Article | ||||||||
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Subjects: | H Social Sciences > HV Social pathology. Social and public welfare R Medicine > RA Public aspects of medicine R Medicine > RB Pathology R Medicine > RC Internal medicine |
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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SWORD Depositor: | Library Publications Router | ||||||||
Library of Congress Subject Headings (LCSH): | Family violence , Women -- Violence against, Marital violence , Central nervous system -- Diseases -- Diagnosis, Pain -- Diagnosis | ||||||||
Journal or Publication Title: | European Journal of Pain | ||||||||
Publisher: | Elsevier Ltd. | ||||||||
ISSN: | 1090-3801 | ||||||||
Official Date: | June 2021 | ||||||||
Dates: |
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Volume: | 25 | ||||||||
Number: | 6 | ||||||||
Page Range: | pp. 1283-1291 | ||||||||
DOI: | 10.1002/ejp.1750 | ||||||||
Status: | Peer Reviewed | ||||||||
Publication Status: | Published | ||||||||
Access rights to Published version: | Open Access (Creative Commons) | ||||||||
Date of first compliant deposit: | 21 June 2021 | ||||||||
Date of first compliant Open Access: | 22 June 2021 | ||||||||
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