The Library
The incidence and prevalence of inflammatory bowel disease in UK primary care: a retrospective cohort study of the IQVIA Medical Research Database
Tools
Tools
Tools
Freeman, Karoline, Ryan, Ronan, Parsons, Nicholas R., Taylor-Phillips, Sian, Willis, Brian H. and Clarke, Aileen (2021) The incidence and prevalence of inflammatory bowel disease in UK primary care: a retrospective cohort study of the IQVIA Medical Research Database. BMC Gastroenterology, 21 (1). 139. doi:10.1186/s12876-021-01716-6
|
PDF
WRAP-incidence-prevalence-inflammatory-bowel-disease-UK-primary-care-retrospective-cohort-study-IQVIA-Medical-Research-Database-2021.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution 4.0. Download (1134Kb) | Preview |
Official URL: http://dx.doi.org/10.1186/s12876-021-01716-6
Abstract
Background:
Our knowledge of the incidence and prevalence of inflammatory bowel disease (IBD) is uncertain. Recent studies reported an increase in prevalence. However, they excluded a high proportion of ambiguous cases from general practice. Estimates are needed to inform health care providers who plan the provision of services for IBD patients. We aimed to estimate the IBD incidence and prevalence in UK general practice.
Methods:
We undertook a retrospective cohort study of routine electronic health records from the IQVIA Medical Research Database covering 14 million patients. Adult patients from 2006 to 2016 were included. IBD was defined as an IBD related Read code or record of IBD specific medication. Annual incidence and 12-month period prevalence were calculated.
Results:
The prevalence of IBD increased between 2006 and 2016 from 106.2 (95% CI 105.2–107.3) to 142.1 (95% CI 140.7–143.5) IBD cases per 10,000 patients which is a 33.8% increase. Incidence varied across the years. The incidence across the full study period was 69.5 (95% CI 68.6–70.4) per 100,000 person years.
Conclusions:
In this large study we found higher estimates of IBD incidence and prevalence than previously reported. Estimates are highly dependent on definitions of disease and previously may have been underestimated.
| Item Type: | Journal Article | ||||||
|---|---|---|---|---|---|---|---|
| Subjects: | R Medicine > RA Public aspects of medicine R Medicine > RC Internal medicine |
||||||
| Divisions: | Faculty of Medicine > Warwick Medical School > Health Sciences Faculty of Medicine > Warwick Medical School |
||||||
| Library of Congress Subject Headings (LCSH): | Inflammatory bowel diseases , Inflammatory bowel diseases -- Diagnosis | ||||||
| Journal or Publication Title: | BMC Gastroenterology | ||||||
| Publisher: | BioMed Central Ltd. | ||||||
| ISSN: | 1471-230X | ||||||
| Official Date: | 26 March 2021 | ||||||
| Dates: |
|
||||||
| Volume: | 21 | ||||||
| Number: | 1 | ||||||
| Article Number: | 139 | ||||||
| DOI: | 10.1186/s12876-021-01716-6 | ||||||
| Status: | Peer Reviewed | ||||||
| Publication Status: | Published | ||||||
| Access rights to Published version: | Open Access | ||||||
| RIOXX Funder/Project Grant: |
|
Request changes or add full text files to a record
Repository staff actions (login required)
 |
View Item |
Downloads
Downloads per month over past year
