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Brain injury after cardiac arrest
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Perkins, Gavin D., Callaway, Clifton W., Haywood, Kirstie L., Neumar, Robert W, Lilja, Gisela, Rowland, Matthew J., Sawyer, Kelly N., Skrifvars, Markus B. and Nolan, Jerry P. (2021) Brain injury after cardiac arrest. The Lancet, 398 (10307). pp. 1195-1278. doi:10.1016/S0140-6736(21)00953-3
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Official URL: https://doi.org/10.1016/S0140-6736(21)00953-3
Abstract
As more people are surviving cardiac arrest, focus needs to shift towards improving neurological outcomes and quality of life in survivors. Brain injury after resuscitation, a common sequela following cardiac arrest, ranges in severity from mild impairment to devastating brain injury and brainstem death. Effective strategies to minimise brain injury after resuscitation include early intervention with cardiopulmonary resuscitation and defibrillation, restoration of normal physiology, and targeted temperature management. It is important to identify people who might have a poor outcome, to enable informed choices about continuation or withdrawal of life-sustaining treatments. Multimodal prediction guidelines seek to avoid premature withdrawal in those who might survive with a good neurological outcome, or prolonging treatment that might result in survival with severe disability. Approximately one in three admitted to intensive care will survive, many of whom will need intensive, tailored rehabilitation after discharge to have the best outcomes.
| Item Type: | Journal Article | ||||||||
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| Subjects: | R Medicine > RC Internal medicine | ||||||||
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Warwick Research in Nursing |
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| Library of Congress Subject Headings (LCSH): | Cardiac arrest -- Complications, Cardiac resuscitation, Brain damage, Brain -- Wounds and injuries, Resuscitation | ||||||||
| Journal or Publication Title: | The Lancet | ||||||||
| Publisher: | Lancet Publishing Group | ||||||||
| ISSN: | 0140-6736 | ||||||||
| Official Date: | 2 October 2021 | ||||||||
| Dates: |
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| Volume: | 398 | ||||||||
| Number: | 10307 | ||||||||
| Page Range: | pp. 1195-1278 | ||||||||
| DOI: | 10.1016/S0140-6736(21)00953-3 | ||||||||
| Status: | Peer Reviewed | ||||||||
| Publication Status: | Published | ||||||||
| Access rights to Published version: | Restricted or Subscription Access | ||||||||
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