UNSPECIFIED (1998) Superoxide electrode based on covalently immobilized cytochrome c: Modelling studies. FREE RADICAL BIOLOGY AND MEDICINE, 25 (8). pp. 973-978. ISSN 0891-5849

Full text not available from this repository.

Abstract

We have recently described an optimised electrode for the detection of enzymatic and cellular superoxide (O-2(.-)) production based on cytochrome c immobilized covalently at a surface-modified gold electrode and applied this system to the study of free radical production by activated human glioblastoma cells. In this paper we report the development of a mathematical model for the O-2(.-) electrode responding to enzymically produced O-2(.-) which should enable the determination of absolute concentrations of O-2(.-) in biological systems when this electrode is employed for direct, real-time monitoring of free radical release and interactions. (C) 1998 Elsevier Science Inc.

Item Type:	Journal Article
Subjects:	Q Science > QD Chemistry R Medicine > RC Internal medicine
Journal or Publication Title:	FREE RADICAL BIOLOGY AND MEDICINE
Publisher:	PERGAMON-ELSEVIER SCIENCE LTD
ISSN:	0891-5849
Date:	15 November 1998
Volume:	25
Number:	8
Number of Pages:	6
Page Range:	pp. 973-978
Publication Status:	Published
URI:	http://wrap.warwick.ac.uk/id/eprint/15188

Data sourced from Thomson Reuters' Web of Knowledge

Request changes to a record

Actions (login required)

View Item