Superoxide electrode based on covalently immobilized cytochrome c: Modelling studies
UNSPECIFIED (1998) Superoxide electrode based on covalently immobilized cytochrome c: Modelling studies. FREE RADICAL BIOLOGY AND MEDICINE, 25 (8). pp. 973-978. ISSN 0891-5849Full text not available from this repository.
We have recently described an optimised electrode for the detection of enzymatic and cellular superoxide (O-2(.-)) production based on cytochrome c immobilized covalently at a surface-modified gold electrode and applied this system to the study of free radical production by activated human glioblastoma cells. In this paper we report the development of a mathematical model for the O-2(.-) electrode responding to enzymically produced O-2(.-) which should enable the determination of absolute concentrations of O-2(.-) in biological systems when this electrode is employed for direct, real-time monitoring of free radical release and interactions. (C) 1998 Elsevier Science Inc.
|Item Type:||Journal Article|
|Subjects:||Q Science > QD Chemistry
R Medicine > RC Internal medicine
|Journal or Publication Title:||FREE RADICAL BIOLOGY AND MEDICINE|
|Publisher:||PERGAMON-ELSEVIER SCIENCE LTD|
|Date:||15 November 1998|
|Number of Pages:||6|
|Page Range:||pp. 973-978|
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