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Naturally occurring terpenes : a promising class of organic molecules to address influenza pandemics

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Al-Salihi, Suhad A. A. and Alberti, Fabrizio (2021) Naturally occurring terpenes : a promising class of organic molecules to address influenza pandemics. Natural Products and Bioprospecting, 11 . pp. 405-419. doi:10.1007/s13659-021-00306-z ISSN 2192-2195.

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Official URL: http://dx.doi.org/10.1007/s13659-021-00306-z

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Abstract

Since the olden times, infectious diseases have largely affected human existence. The newly emerged infections are excessively caused by viruses that are largely associated with mammal reservoirs. The casualties of these emergencies are significantly influenced by the way human beings interact with the reservoirs, especially the animal ones. In our review we will consider the evolutionary and the ecological scales of such infections and their consequences on the public health, with a focus on the pathogenic influenza A virus. The nutraceutical properties of fungal and plant terpene-like molecules will be linked to their ability to lessen the symptoms of viral infections and shed light on their potential use in the development of new drugs. New challenging methods in antiviral discovery will also be discussed in this review. The authors believe that pharmacognosy is the “wave of future pharmaceuticals”, as it can be continually produced and scaled up under eco-friendly requirements. Further diagnostic methods and strategies however are required to standardise those naturally occurring resources.

Item Type: Journal Article
Subjects: Q Science > QP Physiology
R Medicine > RA Public aspects of medicine
R Medicine > RC Internal medicine
R Medicine > RM Therapeutics. Pharmacology
Divisions: Faculty of Science, Engineering and Medicine > Science > Chemistry
Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- )
Library of Congress Subject Headings (LCSH): Influenza A virus , Influenza A virus -- Prevention, Influenza A virus -- Immunological aspects, Terpenes , Antiviral agents
Journal or Publication Title: Natural Products and Bioprospecting
Publisher: Springer
ISSN: 2192-2195
Official Date: August 2021
Dates:
DateEvent
August 2021Published
3 May 2021Available
12 April 2021Accepted
Volume: 11
Page Range: pp. 405-419
DOI: 10.1007/s13659-021-00306-z
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access (Creative Commons)
Date of first compliant deposit: 6 May 2021
Date of first compliant Open Access: 10 May 2021
RIOXX Funder/Project Grant:
Project/Grant IDRIOXX Funder NameFunder ID
ECF-2018-691Leverhulme Trusthttp://dx.doi.org/10.13039/501100000275
Early Career FellowshipUniversity of Warwickhttp://dx.doi.org/10.13039/501100000741

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