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Enantioselective synthesis of epoxides and aziridines by asymmetric methylidene transfer from a sulfimide to carbonyl compounds and imines

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UNSPECIFIED (1998) Enantioselective synthesis of epoxides and aziridines by asymmetric methylidene transfer from a sulfimide to carbonyl compounds and imines. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (20). pp. 3399-3403. ISSN 0300-922X

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Abstract

The sodium salt of sulfimide 2 is a useful asymmetric methylidene transfer agent for the synthesis of enantiomerically enriched epoxides and aziridines. Moderate enantioselectivities are observed with a broad range of carbonyl compounds and with imines. An enantiomerically enriched beta-adrenoreceptor agonist analogue was prepared using the new method.

Item Type: Journal Article
Subjects: Q Science > QD Chemistry
Journal or Publication Title: JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
Publisher: ROYAL SOC CHEMISTRY
ISSN: 0300-922X
Date: 21 October 1998
Number: 20
Number of Pages: 5
Page Range: pp. 3399-3403
Publication Status: Published
URI: http://wrap.warwick.ac.uk/id/eprint/15239

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