The role of copper and iron ions in the gamma-radiolysis of DNA. Part 1. EPR studies at cryogenic temperatures
UNSPECIFIED. (1998) The role of copper and iron ions in the gamma-radiolysis of DNA. Part 1. EPR studies at cryogenic temperatures. RADIATION PHYSICS AND CHEMISTRY, 53 (5). pp. 491-499.Full text not available from this repository.
The gamma-radiolysis of frozen aqueous solutions of DNA has been studied by EPR. The effect of transition metal ions Fe(III) and Cu(II) up to 5 mM concentration emerged in lowering of the total radical production in DNA. The loss of 5-thymyl radical (TH)-T-. was mainly observed (on annealing to 203 K) giving evidence that less radical anion of thymine was formed and that no electron transfer from C.- to thymine was revealed in the system. Fe(III) ions are more efficient in the DNA protection than Cu(II) ions. The specific binding sites of iron ions appear to be thymine base. (C) 1998 Elsevier Science Ltd. All rights reserved.
|Item Type:||Journal Article|
|Subjects:||Q Science > QD Chemistry
Q Science > QC Physics
|Journal or Publication Title:||RADIATION PHYSICS AND CHEMISTRY|
|Publisher:||PERGAMON-ELSEVIER SCIENCE LTD|
|Official Date:||November 1998|
|Number of Pages:||9|
|Page Range:||pp. 491-499|
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