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Assessing the extent of community spread caused by mink-derived SARS-CoV-2 variants
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Wang, Liang, Didelot, Xavier, Bi, Yuhai and Gao, George F. (2021) Assessing the extent of community spread caused by mink-derived SARS-CoV-2 variants. The Innovation . 100128. doi:10.1016/j.xinn.2021.100128 ISSN 2666-6758.
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WRAP-Assessing-extent-community-spread-caused-mink-derived-SARS-CoV-2-2021.pdf - Accepted Version - Requires a PDF viewer. Available under License Creative Commons Attribution Non-commercial No Derivatives 4.0. Download (1861Kb) | Preview |
Official URL: https://doi.org/10.1016/j.xinn.2021.100128
Abstract
SARS-CoV-2 has recently been found to have spread from humans to minks and then to have transmitted back to humans. However, it is unknown to what extent the human-to-human transmission caused by the variant has reached. Here, we used publicly available SARS-CoV-2 genomic sequences from both humans and minks collected in Denmark and Netherlands, and combined phylogenetic analysis with Bayesian inference under an epidemiological model to trace the possibility of person-to-person transmission. The results showed that at least 12.5% of all people being infected with dominated mink-derived SARS-CoV-2 variants in Denmark and Netherlands were caused by human-to-human transmission, indicating this “back-to-human” SARS-CoV-2 variant has already caused human-to-human transmission. Our study also indicated the need for monitoring this mink-derived and other animal source “back-to-human” SARS-CoV-2 in future and that prevention and control measures should be tailored to avoid large-scale community transmission caused by the virus jumped between animals and humans.
Item Type: | Journal Article | ||||||||||||||||||
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Subjects: | Q Science > QL Zoology R Medicine > RA Public aspects of medicine R Medicine > RC Internal medicine |
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Divisions: | Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) | ||||||||||||||||||
SWORD Depositor: | Library Publications Router | ||||||||||||||||||
Library of Congress Subject Headings (LCSH): | COVID-19 (Disease), COVID-19 (Disease) -- Epidemiology, COVID-19 (Disease) -- Transmission, Minks -- Virus diseases -- Transmission, Communicable diseases , Emerging infectious diseases | ||||||||||||||||||
Journal or Publication Title: | The Innovation | ||||||||||||||||||
Publisher: | Elsevier | ||||||||||||||||||
ISSN: | 2666-6758 | ||||||||||||||||||
Official Date: | 7 June 2021 | ||||||||||||||||||
Dates: |
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Article Number: | 100128 | ||||||||||||||||||
DOI: | 10.1016/j.xinn.2021.100128 | ||||||||||||||||||
Status: | Peer Reviewed | ||||||||||||||||||
Publication Status: | Published | ||||||||||||||||||
Access rights to Published version: | Open Access (Creative Commons) | ||||||||||||||||||
Date of first compliant deposit: | 11 June 2021 | ||||||||||||||||||
Date of first compliant Open Access: | 11 June 2021 | ||||||||||||||||||
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