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Synthesis of the C9-C25 fragment of L-755,807. Evidence for the relative configuration of the side-chain.

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UNSPECIFIED (1998) Synthesis of the C9-C25 fragment of L-755,807. Evidence for the relative configuration of the side-chain. TETRAHEDRON LETTERS, 39 (33). pp. 6033-6036. ISSN 0040-4039

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Abstract

Both diastereomers of the side-chain model (2) and C9-C25 fragment (3) of the B2 selective Bradykinin inhibitor L-755,807 have been prepared and their C-13 data compared to those of the natural product and those theoretically predicted by a combination of molecular mechanics and SOS-DFPT/IGLO calculations. The data suggest that the relative configuration of the C23 and C24 methyl groups is syn. (C) 1998 Elsevier Science Ltd. All rights reserved.

Item Type: Journal Article
Subjects: Q Science > QD Chemistry
Journal or Publication Title: TETRAHEDRON LETTERS
Publisher: PERGAMON-ELSEVIER SCIENCE LTD
ISSN: 0040-4039
Date: 13 August 1998
Volume: 39
Number: 33
Number of Pages: 4
Page Range: pp. 6033-6036
Publication Status: Published
URI: http://wrap.warwick.ac.uk/id/eprint/15518

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