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The use of phosphinamide N-protecting groups in the diastereoselective reduction of ketones.

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UNSPECIFIED. (1998) The use of phosphinamide N-protecting groups in the diastereoselective reduction of ketones. TETRAHEDRON, 54 (30). pp. 8827-8840. ISSN 0040-4020

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Abstract

The phosphinamide N-protecting group is demonstrated to be an effective directing group for diastereoselective reductions of proximal ketones. A range of methods for the preparation of the requisite alpha-amino ketones substrates are described (C) 1998 Elsevier Science Ltd. AII rights reserved.

Item Type: Journal Article
Subjects: Q Science > QD Chemistry
Journal or Publication Title: TETRAHEDRON
Publisher: PERGAMON-ELSEVIER SCIENCE LTD
ISSN: 0040-4020
Date: 23 July 1998
Volume: 54
Number: 30
Number of Pages: 14
Page Range: pp. 8827-8840
Publication Status: Published
URI: http://wrap.warwick.ac.uk/id/eprint/15572

Data sourced from Thomson Reuters' Web of Knowledge

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