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Tracking the introduction and spread of SARS-CoV-2 in coastal Kenya
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(2021) Tracking the introduction and spread of SARS-CoV-2 in coastal Kenya. Nature Communications, 12 . 4809 . doi:10.1038/s41467-021-25137-x
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Official URL: https://doi.org/10.1038/s41467-021-25137-x
Abstract
Genomic surveillance of SARS-CoV-2 is important for understanding both the evolution and the patterns of local and global transmission. Here, we generated 311 SARS-CoV-2 genomes from samples collected in coastal Kenya between 17th March and 31st July 2020. We estimated multiple independent SARS-CoV-2 introductions into the region were primarily of European origin, although introductions could have come through neighbouring countries. Lineage B.1 accounted for 74% of sequenced cases. Lineages A, B and B.4 were detected in screened individuals at the Kenya-Tanzania border or returning travellers. Though multiple lineages were introduced into coastal Kenya following the initial confirmed case, none showed extensive local expansion other than lineage B.1. International points of entry were important conduits of SARS-CoV-2 importations into coastal Kenya and early public health responses prevented established transmission of some lineages. Undetected introductions through points of entry including imports from elsewhere in the country gave rise to the local epidemic at the Kenyan coast.
| Item Type: | Journal Article | ||||||||||||||||||
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| Subjects: | R Medicine > RA Public aspects of medicine | ||||||||||||||||||
| Divisions: | Faculty of Science > Life Sciences (2010- ) | ||||||||||||||||||
| Library of Congress Subject Headings (LCSH): | Epidemiology, SARS (Disease) -- coastal Kenya, COVID-19 (Disease), Virus diseases -- Transmission -- coastal Kenya, Phylogeny | ||||||||||||||||||
| Journal or Publication Title: | Nature Communications | ||||||||||||||||||
| Publisher: | Nature Publishing Group | ||||||||||||||||||
| ISSN: | 2041-1723 | ||||||||||||||||||
| Official Date: | 10 August 2021 | ||||||||||||||||||
| Dates: |
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| Volume: | 12 | ||||||||||||||||||
| Article Number: | 4809 | ||||||||||||||||||
| DOI: | 10.1038/s41467-021-25137-x | ||||||||||||||||||
| Status: | Peer Reviewed | ||||||||||||||||||
| Publication Status: | Published | ||||||||||||||||||
| Access rights to Published version: | Open Access | ||||||||||||||||||
| RIOXX Funder/Project Grant: |
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