UNSPECIFIED. (1998) Seroepidemiological study of respiratory syncytial virus in Sao Paulo State, Brazil. JOURNAL OF MEDICAL VIROLOGY, 55 (3). pp. 234-239. ISSN 0146-6615

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Abstract

Transmission of respiratory syncytial virus is thought to be highly seasonal based on reported clinical cases, although transmission resulting in mild disease in all age groups has been little studied. This has been investigated in a seroepidemiological survey using sera from Sao Paulo, Brazil. Seroprevalence was found to increase rapidly with age, reaching over 90% by three years of age. This is typical of viral infections, which produce life-long immunity following primary infection. One-hundred percent seropositivity was attained by five years of age and maintained throughout adulthood, whereas mean antibody titers continued to increase with age. The mean duration of maternal antibodies was estimated to be 3.3 months with antibody decay demonstrated in paired samples from infants. The results are discussed in relation to possible mechanisms generating such a profile. (C) 1998 Wiley-Liss, Inc.

Item Type:	Journal Article
Subjects:	Q Science > QR Microbiology > QR355 Virology
Journal or Publication Title:	JOURNAL OF MEDICAL VIROLOGY
Publisher:	WILEY-LISS
ISSN:	0146-6615
Date:	July 1998
Volume:	55
Number:	3
Number of Pages:	6
Page Range:	pp. 234-239
Publication Status:	Published
URI:	http://wrap.warwick.ac.uk/id/eprint/15696

Data sourced from Thomson Reuters' Web of Knowledge

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