Seroepidemiological study of respiratory syncytial virus in Sao Paulo State, Brazil
UNSPECIFIED (1998) Seroepidemiological study of respiratory syncytial virus in Sao Paulo State, Brazil. JOURNAL OF MEDICAL VIROLOGY, 55 (3). pp. 234-239. ISSN 0146-6615Full text not available from this repository.
Transmission of respiratory syncytial virus is thought to be highly seasonal based on reported clinical cases, although transmission resulting in mild disease in all age groups has been little studied. This has been investigated in a seroepidemiological survey using sera from Sao Paulo, Brazil. Seroprevalence was found to increase rapidly with age, reaching over 90% by three years of age. This is typical of viral infections, which produce life-long immunity following primary infection. One-hundred percent seropositivity was attained by five years of age and maintained throughout adulthood, whereas mean antibody titers continued to increase with age. The mean duration of maternal antibodies was estimated to be 3.3 months with antibody decay demonstrated in paired samples from infants. The results are discussed in relation to possible mechanisms generating such a profile. (C) 1998 Wiley-Liss, Inc.
|Item Type:||Journal Article|
|Subjects:||Q Science > QR Microbiology > QR355 Virology|
|Journal or Publication Title:||JOURNAL OF MEDICAL VIROLOGY|
|Number of Pages:||6|
|Page Range:||pp. 234-239|
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