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Economic costs at age five associated with very preterm birth : multinational European cohort study
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Kim, Sung Wook, Andronis, Lazaros, Seppanen, Anna-Veera, Aubert, Adrien M., Zeitlin, Jennifer, Barros, Henrique, Draper, Elizabeth S. and Petrou, Stavros (2022) Economic costs at age five associated with very preterm birth : multinational European cohort study. Pediatric Research, 92 . pp. 700-711. doi:10.1038/s41390-021-01769-z ISSN 0031-3998 .
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Official URL: https://doi.org/10.1038/s41390-021-01769-z
Abstract
Background
This study aims to estimate the economic costs of care provided to children born very preterm and extremely preterm across 11 European countries, and to understand what perinatal and socioeconomic factors contribute to higher costs.
Methods
Generalised linear modelling was used to explore the association between perinatal and sociodemographic characteristics and total economic costs (€, 2016 prices) during the fifth year of life.
Results
Lower gestational age was associated with increased mean societal costs of €2755 (p < 0.001), €752 (p < 0.01) and €657 (p < 0.01) for children born at < 26, 26–27 and 28–29 weeks, respectively, in comparison to the reference group born at 30–31 weeks. A sensitivity analyses that excluded variables (BPD, any neonatal morbidity and presence of congenital anomaly) plausibly lying on the causal pathway between gestational age at birth and economic outcomes elevated incremental societal costs by €1482, €763 and €144 at < 26, 26–27 and 28–29 weeks, respectively, in comparison to the baseline model.
Conclusion
This study provides new evidence about the main cost drivers associated with preterm birth in European countries. Evidence identified by this study can act as inputs within cost-effectiveness models for preventive or treatment interventions for preterm birth.
Item Type: | Journal Article | ||||||||||||
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Subjects: | H Social Sciences > HQ The family. Marriage. Woman R Medicine > RA Public aspects of medicine R Medicine > RJ Pediatrics |
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | ||||||||||||
Library of Congress Subject Headings (LCSH): | Prematurely born children -- Economic aspects -- Europe, Medical care, Cost of -- Europe, Pediatrics -- Economic aspects -- Europe | ||||||||||||
Journal or Publication Title: | Pediatric Research | ||||||||||||
Publisher: | Nature Publishing Group | ||||||||||||
ISSN: | 0031-3998 | ||||||||||||
Official Date: | September 2022 | ||||||||||||
Dates: |
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Volume: | 92 | ||||||||||||
Page Range: | pp. 700-711 | ||||||||||||
DOI: | 10.1038/s41390-021-01769-z | ||||||||||||
Status: | Peer Reviewed | ||||||||||||
Publication Status: | Published | ||||||||||||
Access rights to Published version: | Open Access (Creative Commons) | ||||||||||||
Date of first compliant deposit: | 23 September 2021 | ||||||||||||
Date of first compliant Open Access: | 8 December 2021 | ||||||||||||
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