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Severe Covid-19 vaccine side-effects are rare in older adults yet are linked with depressive symptoms

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Hoffman, Y., Palgi, P., Goodwin, Robin, Ben-Ezra, Menachem and Greenblatt-Kimron, L. (2022) Severe Covid-19 vaccine side-effects are rare in older adults yet are linked with depressive symptoms. American Journal of Geriatric Psychiatry, 30 (1). pp. 115-116. doi:10.1016/j.jagp.2021.09.010

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Official URL: https://doi.org/10.1016/j.jagp.2021.09.010

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Abstract

COVID-19 vaccine development should have been the “light at the end of the tunnel.” However, antivaccinations attitudes and hesitation are common,1 even among older adults. Such hesitancy has been positively associated with depression, potentially due to concerns about vaccine side-effects.2 We tested the association between depression and vaccine side-effects in older adults, and hypothesized that, like physical illness,3 depression should increase with each additional side-effect.
This survey was conducted via iPanel (a probability based panel, see4 for additional details) to obtain good representation of vaccinated Israeli older adults (N = 939, mean age 68.9 ± 3.43 [range 65–85]; 59.9% females, 46.9% academic education; 75% married). At time of study (January 25th-February 4th, 2021), respondents were 28.15 ± 9.47 days after the first Pfizer vaccine [BNT162b2mRNA]. Participants completed web-based questionnaires comprising demographics, self-rated health, COVID-19 vaccination side-effects and depressive symptoms. Respondents provided informed consent to procedures approved by the last author's university institutional review board. The extent of suffering from side-effects (reported by the FDA 1

Item Type: Journal Item
Divisions: Faculty of Science, Engineering and Medicine > Science > Psychology
Journal or Publication Title: American Journal of Geriatric Psychiatry
Publisher: Elsevier
ISSN: 1064-7481
Official Date: 1 January 2022
Dates:
DateEvent
1 January 2022Published
30 September 2021Available
23 September 2021Accepted
Volume: 30
Number: 1
Page Range: pp. 115-116
DOI: 10.1016/j.jagp.2021.09.010
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
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