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Chemical ionization of neutral peptides produced by matrix-assisted laser desorption

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UNSPECIFIED (1998) Chemical ionization of neutral peptides produced by matrix-assisted laser desorption. CHEMICAL PHYSICS LETTERS, 284 (5-6). pp. 412-418. ISSN 0009-2614

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Abstract

The cationization in the gas phase of neutral peptides formed under the conditions of matrix-assisted laser desorption (MALD) has been demonstrated. The beam of neutral peptides formed by MALD using one laser was intercepted several hundred micrometers above the sample surface by a beam of cations produced using a second laser. The intensity of cationized neutral gramicidin S formed in this way was comparable to the ion signal produced by conventional matrix-assisted laser desorption/ionization (MALDI). The threshold fluences for MALD of neutral peptides have been shown to be lower than those for formation of ions from the same samples by MALDI. (C) 1998 Elsevier Science B.V.

Item Type: Journal Article
Subjects: Q Science > QD Chemistry
Q Science > QC Physics
Journal or Publication Title: CHEMICAL PHYSICS LETTERS
Publisher: ELSEVIER SCIENCE BV
ISSN: 0009-2614
Date: 6 March 1998
Volume: 284
Number: 5-6
Number of Pages: 7
Page Range: pp. 412-418
Publication Status: Published
URI: http://wrap.warwick.ac.uk/id/eprint/15862

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