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Commentary on the use of the reproduction number R during the COVID-19 pandemic
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(2021) Commentary on the use of the reproduction number R during the COVID-19 pandemic. Statistical Methods in Medical Research . 096228022110370. doi:10.1177/09622802211037079 (In Press)
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WRAP-Commentary-use-reproduction-number-R-COVID-19-pandemic-2021.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution 4.0. Download (1320Kb) | Preview |
Official URL: https://doi.org/10.1177%2F09622802211037079
Abstract
Since the beginning of the COVID-19 pandemic, the reproduction number [Formula: see text] has become a popular epidemiological metric used to communicate the state of the epidemic. At its most basic, [Formula: see text] is defined as the average number of secondary infections caused by one primary infected individual. [Formula: see text] seems convenient, because the epidemic is expanding if [Formula: see text] and contracting if [Formula: see text]. The magnitude of [Formula: see text] indicates by how much transmission needs to be reduced to control the epidemic. Using [Formula: see text] in a naïve way can cause new problems. The reasons for this are threefold: (1) There is not just one definition of [Formula: see text] but many, and the precise definition of [Formula: see text] affects both its estimated value and how it should be interpreted. (2) Even with a particular clearly defined [Formula: see text], there may be different statistical methods used to estimate its value, and the choice of method will affect the estimate. (3) The availability and type of data used to estimate [Formula: see text] vary, and it is not always clear what data should be included in the estimation. In this review, we discuss when [Formula: see text] is useful, when it may be of use but needs to be interpreted with care, and when it may be an inappropriate indicator of the progress of the epidemic. We also argue that careful definition of [Formula: see text], and the data and methods used to estimate it, can make [Formula: see text] a more useful metric for future management of the epidemic.
| Item Type: | Journal Item | |||||||||||||||||||||||||||||||||||||||||||||
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| Subjects: | R Medicine > RA Public aspects of medicine | |||||||||||||||||||||||||||||||||||||||||||||
| Divisions: | Faculty of Science > Mathematics | |||||||||||||||||||||||||||||||||||||||||||||
| SWORD Depositor: | Library Publications Router | |||||||||||||||||||||||||||||||||||||||||||||
| Library of Congress Subject Headings (LCSH): | COVID-19 Pandemic, 2020- , Viruses -- Reproduction, COVID-19 Pandemic, 2020- | |||||||||||||||||||||||||||||||||||||||||||||
| Journal or Publication Title: | Statistical Methods in Medical Research | |||||||||||||||||||||||||||||||||||||||||||||
| Publisher: | SAGE Publications | |||||||||||||||||||||||||||||||||||||||||||||
| ISSN: | 1477-0334 | |||||||||||||||||||||||||||||||||||||||||||||
| Official Date: | 27 September 2021 | |||||||||||||||||||||||||||||||||||||||||||||
| Dates: |
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| Article Number: | 096228022110370 | |||||||||||||||||||||||||||||||||||||||||||||
| DOI: | 10.1177/09622802211037079 | |||||||||||||||||||||||||||||||||||||||||||||
| Status: | Peer Reviewed | |||||||||||||||||||||||||||||||||||||||||||||
| Publication Status: | In Press | |||||||||||||||||||||||||||||||||||||||||||||
| Access rights to Published version: | Open Access | |||||||||||||||||||||||||||||||||||||||||||||
| RIOXX Funder/Project Grant: |
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