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NMR studies of group 8 metallodrugs : 187Os-enriched organo-osmium half-sandwich anticancer complex
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Needham, Russell J., Prokes, Ivan, Habtemariam, Abraha, Romero-Canelón, Isolda, Clarkson, Guy J. and Sadler, Peter J. (2021) NMR studies of group 8 metallodrugs : 187Os-enriched organo-osmium half-sandwich anticancer complex. Dalton Transactions, 50 (37). pp. 12970-12981. doi:10.1039/d1dt02213j
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WRAP-NMR-studies-group-8-metallodrugs-half-sandwich-complex-2021.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution. Download (3294Kb) | Preview |
Official URL: https://doi.org/10.1039/D1DT02213J
Abstract
Synthesis of this 187Os-enriched organo-osmium azopyridine anticancer complex, has allowed determination of 187Os NMR J-couplings to ligand 1H and 13C, and the 187Os chemical shift. The complex was also characterised by X-ray crystallography and MS.
| Item Type: | Journal Article | |||||||||||||||
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| Subjects: | Q Science > QD Chemistry Q Science > QP Physiology R Medicine > R Medicine (General) R Medicine > RC Internal medicine R Medicine > RM Therapeutics. Pharmacology |
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| Divisions: | Faculty of Science > Chemistry | |||||||||||||||
| SWORD Depositor: | Library Publications Router | |||||||||||||||
| Library of Congress Subject Headings (LCSH): | Nuclear magnetic resonance spectroscopy, Metals in medicine, Metal complexes -- Therapeutic use, Cancer -- Treatment, Cancer -- Research, Organoosmium compounds | |||||||||||||||
| Journal or Publication Title: | Dalton Transactions | |||||||||||||||
| Publisher: | Royal Society of Chemistry (RSC) | |||||||||||||||
| ISSN: | 1477-9234 | |||||||||||||||
| Official Date: | 7 October 2021 | |||||||||||||||
| Dates: |
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| Volume: | 50 | |||||||||||||||
| Number: | 37 | |||||||||||||||
| Page Range: | pp. 12970-12981 | |||||||||||||||
| DOI: | 10.1039/d1dt02213j | |||||||||||||||
| Status: | Peer Reviewed | |||||||||||||||
| Publication Status: | Published | |||||||||||||||
| Access rights to Published version: | Open Access | |||||||||||||||
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