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The pneumococcal divisome : dynamic control of streptococcus pneumoniae cell division

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Briggs, Nicholas, Bruce, Kevin E., Naskar, Souvik, Winkler, Malcolm E. and Roper, David I. (2021) The pneumococcal divisome : dynamic control of streptococcus pneumoniae cell division. Frontiers in Microbiology, 12 . 737396. doi:10.3389/fmicb.2021.737396 ISSN 1664-302X.

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Official URL: http://dx.doi.org/10.3389/fmicb.2021.737396

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Abstract

Cell division in Streptococcus pneumoniae (pneumococcus) is performed and regulated by a protein complex consisting of at least 14 different protein elements; known as the divisome. Recent findings have advanced our understanding of the molecular events surrounding this process and have provided new understanding of the mechanisms that occur during the division of pneumococcus. This review will provide an overview of the key protein complexes and how they are involved in cell division. We will discuss the interaction of proteins in the divisome complex that underpin the control mechanisms for cell division and cell wall synthesis and remodelling that are required in S. pneumoniae, including the involvement of virulence factors and capsular polysaccharides.

Item Type: Journal Article
Subjects: Q Science > QR Microbiology > QR180 Immunology
Divisions: Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- )
Library of Congress Subject Headings (LCSH): Streptococcus pneumoniae, Cell division, Peptidoglycans -- Synthesis
Journal or Publication Title: Frontiers in Microbiology
Publisher: Frontiers Research Foundation
ISSN: 1664-302X
Official Date: 18 October 2021
Dates:
DateEvent
18 October 2021Published
15 September 2021Accepted
Volume: 12
Article Number: 737396
DOI: 10.3389/fmicb.2021.737396
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access (Creative Commons)
Date of first compliant deposit: 26 October 2021
Date of first compliant Open Access: 26 October 2021
RIOXX Funder/Project Grant:
Project/Grant IDRIOXX Funder NameFunder ID
MR/N014294/1[MRC] Medical Research Councilhttp://dx.doi.org/10.13039/501100000265

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