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Challenges in modeling the emergence of novel pathogens

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Glennon, Emma E., Bruijning, Marjolein, Lessler, Justin, Miller, Ian F., Rice, Benjamin L., Thompson, Robin N., Wells, Konstans and Metcalf, C. Jessica E. (2021) Challenges in modeling the emergence of novel pathogens. Epidemics, 37 . 100516. doi:10.1016/j.epidem.2021.100516

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Official URL: http://dx.doi.org/10.1016/j.epidem.2021.100516

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Abstract

The emergence of infectious agents with pandemic potential present scientific challenges from detection to data interpretation to understanding determinants of risk and forecasts. Mathematical models could play an essential role in how we prepare for future emergent pathogens. Here, we describe core directions for expansion of the existing tools and knowledge base, including: using mathematical models to identify critical directions and paths for strengthening data collection to detect and respond to outbreaks of novel pathogens; expanding basic theory to identify infectious agents and contexts that present the greatest risks, over both the short and longer term; by strengthening estimation tools that make the most use of the likely range and uncertainties in existing data; and by ensuring modelling applications are carefully communicated and developed within diverse and equitable collaborations for increased public health benefit.

Item Type: Journal Article
Subjects: Q Science > QA Mathematics
Q Science > QA Mathematics > QA76 Electronic computers. Computer science. Computer software
Q Science > QH Natural history
Divisions: Faculty of Science > Mathematics
Library of Congress Subject Headings (LCSH): Pathogenic microorganisms, Pathogenic microorganisms -- Detection -- Mathematic models, Genotype-environment interaction , Genotype-environment interaction -- Mathematic models, Big data
Journal or Publication Title: Epidemics
Publisher: Elsevier BV
ISSN: 1755-4365
Official Date: December 2021
Dates:
DateEvent
December 2021Published
25 October 2021Available
22 October 2021Accepted
Volume: 37
Article Number: 100516
DOI: 10.1016/j.epidem.2021.100516
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access
RIOXX Funder/Project Grant:
Project/Grant IDRIOXX Funder NameFunder ID
EP/R014604/1[EPSRC] Engineering and Physical Sciences Research Councilhttp://dx.doi.org/10.13039/501100000266
019.192EN.017[NWO] Nederlandse Organisatie voor Wetenschappelijk Onderzoekhttp://dx.doi.org/10.13039/501100003246
UNSPECIFIEDPrinceton Universityhttp://dx.doi.org/10.13039/100006734
220463/Z/20/ZWellcome Trusthttp://dx.doi.org/10.13039/100010269

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