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Synthetic and mass spectral fragmentation studies on trisubstituted 2H-pyran-2-ones and comparative EIMS behaviour of biologically active 3,5-disubstituted pyrazoles and isoxazoles
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UNSPECIFIED (1997) Synthetic and mass spectral fragmentation studies on trisubstituted 2H-pyran-2-ones and comparative EIMS behaviour of biologically active 3,5-disubstituted pyrazoles and isoxazoles. INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 36 (10). pp. 872-879. ISSN 0376-4699
Full text not available from this repository.Abstract
Eight 3-cyano-4-thiomethyl-6-aryl-2H-pyran-2-ones 1-8 and three 3-cyano-4-(N,N-dimethyl)amino-6-aryl-2H-pyran-2-ones 9-11 have been synthesised and their detailed mass fragmentation pattern alongwith the X-ray crystal structure of a novel pyrone 5 have been studied. In addition, a comparative EIMS behaviour of 3,5-disubstituted pyrazoles 16-23 and isoxazoles 12-15 is reported. The pyrazole derivative 23 has been found to possess strong anti-invasive activity against human breast carcinoma cells.
| Item Type: | Journal Article |
|---|---|
| Subjects: | Q Science > QD Chemistry |
| Journal or Publication Title: | INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY |
| Publisher: | NATL INST SCIENCE COMMUNICATION |
| ISSN: | 0376-4699 |
| Date: | October 1997 |
| Volume: | 36 |
| Number: | 10 |
| Number of Pages: | 8 |
| Page Range: | pp. 872-879 |
| Publication Status: | Published |
| URI: | http://wrap.warwick.ac.uk/id/eprint/16064 |
Data sourced from Thomson Reuters' Web of Knowledge
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