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Detection of SARS-CoV-2 variant 501Y.V2 in Comoros Islands in January 2021 [version 1; peer review: 2 approved]
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(2022) Detection of SARS-CoV-2 variant 501Y.V2 in Comoros Islands in January 2021 [version 1; peer review: 2 approved]. Wellcome Open Research, 6 . 192. doi:10.12688/wellcomeopenres.16889.1 ISSN 2398-502X.
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WRAP-Detection-SARS-CoV-2-variant-Comoros-Islands-January-2021.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution 4.0. Download (1282Kb) | Preview |
Official URL: https://doi.org/10.12688/wellcomeopenres.16889.1
Abstract
Background. Genomic data is key in understanding the spread and evolution of SARS-CoV-2 pandemic and informing the design and evaluation of interventions. However, SARS-CoV-2 genomic data remains scarce across Africa, with no reports yet from the Indian Ocean islands. Methods. We genome sequenced six SARS-CoV-2 positive samples from the first major infection wave in the Union of Comoros in January 2021 and undertook detailed phylogenetic analysis. Results. All the recovered six genomes classified within the 501Y.V2 variant of concern (also known as lineage B.1.351) and appeared to be from 2 sub-clusters with the most recent common ancestor dated 30th Oct-2020 (95% Credibility Interval: 06th Sep-2020 to 10th Dec-2020). Comparison of the Comoros genomes with those of 501Y.V2 variant of concern from other countries deposited into the GISAID database revealed their close association with viruses identified in France and Mayotte (part of the Comoros archipelago and a France, Overseas Department). Conclusions. The recovered genomes, albeit few, confirmed local transmission following probably multiple introductions of the SARS-CoV-2 501Y.V2 variant of concern during the Comoros’s first major COVID-19 wave. These findings demonstrate the importance of genomic surveillance and have implications for ongoing control strategies on the islands.
| Item Type: | Journal Article | ||||||||||||
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| Subjects: | R Medicine > RA Public aspects of medicine | ||||||||||||
| Divisions: | Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) | ||||||||||||
| SWORD Depositor: | Library Publications Router | ||||||||||||
| Library of Congress Subject Headings (LCSH): | COVID-19 (Disease), COVID-19 (Disease) -- Epidemiology -- Comoros | ||||||||||||
| Journal or Publication Title: | Wellcome Open Research | ||||||||||||
| Publisher: | F1000 Research Ltd | ||||||||||||
| ISSN: | 2398-502X | ||||||||||||
| Official Date: | 23 March 2022 | ||||||||||||
| Dates: |
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| Volume: | 6 | ||||||||||||
| Article Number: | 192 | ||||||||||||
| DOI: | 10.12688/wellcomeopenres.16889.1 | ||||||||||||
| Status: | Peer Reviewed | ||||||||||||
| Publication Status: | Published | ||||||||||||
| Reuse Statement (publisher, data, author rights): | ** From Crossref journal articles via Jisc Publications Router ** History: epub 28-07-2021; issued 28-07-2021. | ||||||||||||
| Access rights to Published version: | Open Access (Creative Commons) | ||||||||||||
| Date of first compliant deposit: | 25 May 2022 | ||||||||||||
| Date of first compliant Open Access: | 25 May 2022 | ||||||||||||
| RIOXX Funder/Project Grant: |
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