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Virus morphology : insights from super-resolution fluorescence microscopy
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Robb, Nicole C. (2022) Virus morphology : insights from super-resolution fluorescence microscopy. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1868 (4). 166347. doi:10.1016/j.bbadis.2022.166347 ISSN 0925-4439.
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WRAP-Virus-morphology-super-resolution-fluorescence-microscopy-2022.pdf - Accepted Version - Requires a PDF viewer. Available under License Creative Commons Attribution Non-commercial No Derivatives 4.0. Download (1993Kb) | Preview |
Official URL: http://dx.doi.org/10.1016/j.bbadis.2022.166347
Abstract
As epitomised by the COVID-19 pandemic, diseases caused by viruses are one of the greatest health and economic burdens to human society. Viruses are ‘nanostructures’, and their small size (typically less than 200 nm in diameter) can make it challenging to obtain images of their morphology and structure. Recent advances in fluorescence microscopy have given rise to super-resolution techniques, which have enabled the structure of viruses to be visualised directly at a resolution in the order of 20 nm. This mini-review discusses how recent state-of-the-art super-resolution imaging technologies are providing new nanoscale insights into virus structure.
Item Type: | Journal Article | ||||||||||||
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Subjects: | Q Science > QH Natural history Q Science > QR Microbiology |
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | ||||||||||||
Library of Congress Subject Headings (LCSH): | Viruses -- Morphology, Fluorescence microscopy | ||||||||||||
Journal or Publication Title: | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | ||||||||||||
Publisher: | Elsevier BV | ||||||||||||
ISSN: | 0925-4439 | ||||||||||||
Official Date: | 1 April 2022 | ||||||||||||
Dates: |
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Volume: | 1868 | ||||||||||||
Number: | 4 | ||||||||||||
Article Number: | 166347 | ||||||||||||
DOI: | 10.1016/j.bbadis.2022.166347 | ||||||||||||
Status: | Peer Reviewed | ||||||||||||
Publication Status: | Published | ||||||||||||
Access rights to Published version: | Restricted or Subscription Access | ||||||||||||
Date of first compliant deposit: | 25 January 2022 | ||||||||||||
Date of first compliant Open Access: | 25 January 2022 | ||||||||||||
RIOXX Funder/Project Grant: |
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