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Fragile X syndrome : an overview of cause, characteristics, assessment and management

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Crawford, Hayley, Abbeduto, Leonard, Hall, Scott S., Hardiman, Rebecca, Hessl, David, Roberts, Jane E., Scerif, Gaia, Stanfield, Andrew C., Turk, Jeremy and Oliver, Chris (2020) Fragile X syndrome : an overview of cause, characteristics, assessment and management. Paediatrics and Child Health, 30 (11). pp. 400-403. doi:10.1016/j.paed.2020.08.007 ISSN 1751-7222.

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Official URL: http://dx.doi.org/10.1016/j.paed.2020.08.007

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Abstract

Fragile X syndrome (FXS) is the most common identifiable cause of inherited intellectual disability and autism spectrum conditions, and is associated with a range of physical, cognitive and behavioural characteristics. Alongside intellectual disability, heightened rates of autism spectrum disorder, anxiety disorders, attention-deficit-hyperactivity disorder, self-injury and aggression are reported. Timely identification of FXS as well as assessments of common co-morbid psychological conditions and underlying health problems are essential to ensure individuals with FXS receive appropriate support. This article provides an overview for clinicians of current literature on the cause of FXS as well as the key physical, cognitive, and behavioural characteristics with a focus on children and adolescents.

Item Type: Journal Article
Subjects: H Social Sciences > HV Social pathology. Social and public welfare
R Medicine > RC Internal medicine
R Medicine > RJ Pediatrics
Divisions: Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Mental Health and Wellbeing
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Fragile X syndrome , Intellectual disability , Autism spectrum disorders , Anxiety disorders , Attention-deficit hyperactivity disorder
Journal or Publication Title: Paediatrics and Child Health
Publisher: The Medicine Publishing Company
ISSN: 1751-7222
Official Date: November 2020
Dates:
DateEvent
November 2020Published
3 September 2020Available
20 April 2020Accepted
Volume: 30
Number: 11
Page Range: pp. 400-403
DOI: 10.1016/j.paed.2020.08.007
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
Date of first compliant deposit: 21 October 2022
Date of first compliant Open Access: 21 October 2022

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