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Ketamine treatment for depression : qualitative study exploring patient views
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Jilka, Sagar, Odoi, Clarissa Mary, Wilson, Emma, Meran, Sazan, Simblett, Sara and Wykes, Til (2021) Ketamine treatment for depression : qualitative study exploring patient views. BJPsych Open, 7 (1). e32. doi:10.1192/bjo.2020.165 ISSN 2056-4724.
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Official URL: http://dx.doi.org/10.1192/bjo.2020.165
Abstract
Background
Ketamine is a new and promising treatment for depression but comes with challenges to implement because of its potential for abuse.
Aims
We sought the views of patients to inform policy and practical decisions about the clinical use of ketamine before large-scale roll-out is considered.
Method
This qualitative study used three focus groups and three validation sessions from 14 patients with prior diagnoses of depression but no experience of ketamine treatment. Focus groups explored their views about clinical use of ketamine and the best way for ketamine to be administered and monitored. The qualitative data were analysed by three service-user researchers using thematic analysis.
Results
Five themes were generated: changing public perceptions, risks, monitoring, privacy and data protection, and practical aspects. Participants were conscious of the stigma attached to ketamine as a street drug and wanted better public education, and evidence on the safety of ketamine after long-term use. They felt that monitoring was required to provide evidence for ketamine's safe use and administration, but there were concerns about the misuse of this information. Practical aspects included discussions about treatment duration, administration and accessibility (for example who would receive it, under what criteria and how).
Conclusions
Patients are enthusiastic about ketamine treatment but need more information before national roll-out. The wider societal impact of ketamine treatment also needs to be considered and patients need to be part of any future roll-out to ensure its success.
| Item Type: | Journal Article | |||||||||
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| Subjects: | R Medicine > RC Internal medicine R Medicine > RM Therapeutics. Pharmacology R Medicine > RS Pharmacy and materia medica |
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| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Library of Congress Subject Headings (LCSH): | Depressed persons -- Treatment, Mentally ill , Depression, Mental , Antidepressants , Ketamine , Ketamine abuse , Drugs of abuse | |||||||||
| Journal or Publication Title: | BJPsych Open | |||||||||
| Publisher: | Cambridge University Press | |||||||||
| ISSN: | 2056-4724 | |||||||||
| Official Date: | 11 January 2021 | |||||||||
| Dates: |
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| Volume: | 7 | |||||||||
| Number: | 1 | |||||||||
| Article Number: | e32 | |||||||||
| DOI: | 10.1192/bjo.2020.165 | |||||||||
| Status: | Peer Reviewed | |||||||||
| Publication Status: | Published | |||||||||
| Access rights to Published version: | Open Access (Creative Commons) | |||||||||
| Date of first compliant deposit: | 4 March 2022 | |||||||||
| Date of first compliant Open Access: | 4 March 2022 | |||||||||
| RIOXX Funder/Project Grant: |
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| Is Part Of: | 1 |
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