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Impact of the COVID-19 pandemic on in-hospital cardiac arrests in the UK
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Edwards, Julia M., Nolan, Jerry P., Soar, Jasmeet, Smith, Gary B., Reynolds, Emily, Carnall, Jane, Rowan, Kathryn M., Harrison, David A. and Doidge, James C. (2022) Impact of the COVID-19 pandemic on in-hospital cardiac arrests in the UK. Resuscitation, 173 . pp. 4-11. doi:10.1016/j.resuscitation.2022.02.007 ISSN 0300-9572.
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Official URL: https://doi.org/10.1016/j.resuscitation.2022.02.00...
Abstract
To compare in-hospital cardiac arrest (IHCA) rates and patient outcomes during the first COVID-19 wave in the United Kingdom (UK) in 2020 with the same period in previous years. A retrospective, multicentre cohort study of 154 UK hospitals that participate in the National Cardiac Arrest Audit and have intensive care units participating in the Case Mix Programme national audit of intensive care. Hospital burden of COVID-19 was defined by the number of patients with confirmed SARS-CoV2 infection admitted to critical care per 10,000 hospital admissions. 16,474 patients with IHCA where a resuscitation team attended were included. Patients admitted to hospital during 2020 were younger, more often male, and of non-white ethnicity compared with 2016-2019. A decreasing trend in IHCA rates between 2016 and 2019 was reversed in 2020. Hospitals with higher burden of COVID-19 had the greatest difference in IHCA rates (21.8 per 10,000 admissions in April 2020 vs 14.9 per 10,000 in April 2019). The proportions of patients achieving ROSC ≥ 20 min and surviving to hospital discharge were lower in 2020 compared with 2016-19 (46.2% vs 51.2%; and 21.9% vs 22.9%, respectively). Among patients with IHCA, higher hospital burden of COVID-19 was associated with reduced survival to hospital discharge (OR = 0.95; 95% CI 0.93 to 0.98; p < 0.001). In comparison with 2016-2019, the first COVID-19 wave in 2020 was associated with a higher rate of IHCA and decreased survival among patients attended by resuscitation teams. These changes were greatest in hospitals with the highest COVID-19 burden.
| Item Type: | Journal Article | |||||||||
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| Subjects: | R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine R Medicine > RC Internal medicine |
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| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| SWORD Depositor: | Library Publications Router | |||||||||
| Library of Congress Subject Headings (LCSH): | Cardiac arrest -- Great Britain -- Statistics, Cardiac arrest -- Great Britain, COVID-19 (Disease) -- Complications, COVID-19 Pandemic, 2020- | |||||||||
| Journal or Publication Title: | Resuscitation | |||||||||
| Publisher: | Elsevier | |||||||||
| ISSN: | 0300-9572 | |||||||||
| Official Date: | 1 April 2022 | |||||||||
| Dates: |
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| Volume: | 173 | |||||||||
| Page Range: | pp. 4-11 | |||||||||
| DOI: | 10.1016/j.resuscitation.2022.02.007 | |||||||||
| Status: | Peer Reviewed | |||||||||
| Publication Status: | Published | |||||||||
| Access rights to Published version: | Restricted or Subscription Access | |||||||||
| Date of first compliant deposit: | 28 March 2022 | |||||||||
| RIOXX Funder/Project Grant: |
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