Chen, Xuequan, Lindley-Hatcher, Hannah, Stantchev, Rayko I., Wang, Jiarui , Li, Kaidi , Hernandez-Serrano, Arturo I., Taylor, Zachary D. , Castro-Camus, Enrique and Pickwell-MacPherson, Emma (2022) Terahertz (THz) biophotonics technology : instrumentation, techniques, and biomedical applications. Chemical Physics Reviews, 3 (1). 011311. doi:10.1063/5.0068979 ISSN 2688-4070.

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Abstract

Terahertz (THz) technology has experienced rapid development in the past two decades. Growing numbers of interdisciplinary applications are emerging, including material science, physics, communications, security, as well as biomedicine. THz biophotonics involves studies applying THz photonic technology in biomedicine, which has attracted attention due to the unique features of THz waves, such as the high sensitivity to water, resonance with biomolecules, favourable spatial resolution, capacity to probe the water-biomolecule interactions and non-ionizing photon energy. Despite the great potential, THz biophotonics is still at an early stage of development. There is a lack of standards for instrumentation, measurement protocols, and data analysis which makes it difficult to make comparisons among all the work published. In this article we give a comprehensive review of the key findings which have underpinned research into biomedical applications of THz technology. In particular, we will focus on the advances made in general
THz instrumentation and specific THz-based instruments for biomedical applications. We will also discuss the theories describing the interaction between THz light and biomedical samples. We aim to provide an overview of both, basic biomedical research, as well as pre-clinical and clinical applications under investigation. The paper aims to provide a
clear picture of the achievements, challenges and future perspectives of THz biophotonics.

Item Type:	Journal Article
Subjects:	T Technology > TK Electrical engineering. Electronics Nuclear engineering
Divisions:	Faculty of Science, Engineering and Medicine > Science > Physics
Library of Congress Subject Headings (LCSH):	Terahertz technology, Biochemistry, Photonics, Nanotechnology
Journal or Publication Title:	Chemical Physics Reviews
Publisher:	AIP
ISSN:	2688-4070
Official Date:	March 2022
Dates:	Date Event March 2022 Published 24 March 2022 Available 8 February 2022 Accepted 28 August 2021 Submitted
Volume:	3
Number:	1
Article Number:	011311
DOI:	10.1063/5.0068979
Status:	Peer Reviewed
Publication Status:	Published
Reuse Statement (publisher, data, author rights):	The following article has been accepted by Chemical Physics Reviews. After it is published, it will be found at https://aip.scitation.org/doi/10.1063/5.0068979
Access rights to Published version:	Restricted or Subscription Access
Date of first compliant deposit:	7 March 2022
Date of first compliant Open Access:	7 March 2022
RIOXX Funder/Project Grant:	Project/Grant ID RIOXX Funder Name Funder ID EP/S021442/1 [EPSRC] Engineering and Physical Sciences Research Council http://dx.doi.org/10.13039/501100000266 UNSPECIFIED [RS] Royal Society http://dx.doi.org/10.13039/501100000288 14206717 Research Grants Council, University Grants Committee http://dx.doi.org/10.13039/501100002920 61988102 [NSFC] National Natural Science Foundation of China http://dx.doi.org/10.13039/501100001809
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