The Library
Initial experience of temperature-controlled irrigated radiofrequency ablation for ischaemic cardiomyopathy ventricular tachycardia ablation
Tools
Tools
Tools
Al-Sheikhli, Jaffar, Patchett, Ian, Lim, Ven Gee, Marshall, Leeann, Foster, Will, Kuehl, Michael, Yusuf, Shamil, Panikker, Sandeep, Patel, Kiran, Osman, Faizel, Banerjee, Prithwish, Lellouche, Nicolas and Dhanjal, Tarvinder (2022) Initial experience of temperature-controlled irrigated radiofrequency ablation for ischaemic cardiomyopathy ventricular tachycardia ablation. Journal of Interventional Cardiac Electrophysiology : an international journal of arrhythmias and pacing . doi:10.1007/s10840-022-01158-4 ISSN 1572-8595. (In Press)
|
PDF
WRAP-Initial-experience-of-temperature-controlled-irrigated-radiofrequency-ablation-Kuehl-2022.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution 4.0. Download (1057Kb) | Preview |
Official URL: http://dx.doi.org/10.1007/s10840-022-01158-4
Abstract
Background
The DiamondTemp ablation (DTA) catheter system delivers high power, open-irrigated, temperature-controlled radiofrequency (RF) ablation. This novel ablation system has not been previously used for ventricular tachycardia (VT) ablation.
Objective
Feasibility of using the DTA catheter system for VT ablation in ischaemic cardiomyopathy (ICM) patients.
Method
Ten ICM patients with optimal anti-arrhythmic drug therapy and implantable cardiac defibrillators (ICD) were recruited. VT inducibility testing was performed at the end of the procedure. ICD data for device detected VT episodes and device treated VT episodes were collected for 6-months pre- and post-ablation.
Results
Substrate analysis demonstrated reductions in the borderzone area of 4.4 cm2 (p = 0.026) and late potential area of 3.5 cm2 (p = 0.0449) post-ablation, with reductions in the mean bipolar and unipolar voltages of the ablation target areas (0.14 mV (p = 0.0007); 0.59 mV (p = 0.0072) respectively). Complete procedural success was achieved in 9 procedures. Post-ablation VT inducibility testing was not performed in 1 procedure due to a steam pop complication resulting in pericardial tamponade requiring drainage. Mean follow-up of 214 ± 33 days revealed an 88% reduction in total VT episodes (n = 266 median 16 [IQR 3–57] to n = 33 median 0; p = 0.0164) and 77% reduction in ICD therapies (n = 128 median 5 [IQR 2–15] to n = 30 median 0; p = 0.0181).
Conclusion
The DTA system resulted in adequate lesion characteristics with effective substrate modification, acute procedural success and improved outcomes at intermediate-term follow-up. Randomised controlled trials are required to compare the performance of the DTA system against conventional ablation catheters.
| Item Type: | Journal Article | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Subjects: | R Medicine > RC Internal medicine R Medicine > RD Surgery |
||||||||
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | ||||||||
| Library of Congress Subject Headings (LCSH): | Ventricular tachycardia, Catheter ablation, Ventricular tachycardia -- Surgery, Heart -- Ventricles -- Thermotherapy | ||||||||
| Journal or Publication Title: | Journal of Interventional Cardiac Electrophysiology : an international journal of arrhythmias and pacing | ||||||||
| Publisher: | Springer | ||||||||
| ISSN: | 1572-8595 | ||||||||
| Official Date: | 22 February 2022 | ||||||||
| Dates: |
|
||||||||
| Number of Pages: | 9 | ||||||||
| DOI: | 10.1007/s10840-022-01158-4 | ||||||||
| Status: | Peer Reviewed | ||||||||
| Publication Status: | In Press | ||||||||
| Access rights to Published version: | Open Access (Creative Commons) | ||||||||
| Date of first compliant deposit: | 14 March 2022 | ||||||||
| Date of first compliant Open Access: | 16 March 2022 |
Request changes or add full text files to a record
Repository staff actions (login required)
 |
View Item |
Downloads
Downloads per month over past year
