The Library
Stimuli responsive asymmetric catalysis by triggered pseudo-enantiomeric proligand release
Tools
Spring, Sam, Goggins, Sean and Frost, Christopher G. (2022) Stimuli responsive asymmetric catalysis by triggered pseudo-enantiomeric proligand release. Organic & Biomolecular Chemistry, 20 (11). 2194-2199 . doi:10.1039/d2ob00196a ISSN 1477-0520.
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Official URL: https://doi.org/10.1039/d2ob00196a
Abstract
Complex stimuli responsive systems are the basis for molecular machines and computing. A dual psuedo-enantiomer system was conceived, where the combination of two ‘switch-on’ asymmetric catalytic cycles could be selectively triggered to afford an enantioenriched product. Two pseudo-enantiomeric proligands were designed and synthesised for selective activation by fluoride and alkaline phosphatase. The proligands were firstly incorporated into single proligand systems, and then into a dual proligand system, where enantioselectivity of up to 98 : 2 was achieved in the reduction of prochiral ketone following external stimulation.
Item Type: | Journal Article | ||||||
---|---|---|---|---|---|---|---|
Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry | ||||||
SWORD Depositor: | Library Publications Router | ||||||
Journal or Publication Title: | Organic & Biomolecular Chemistry | ||||||
Publisher: | Royal Society of Chemistry | ||||||
ISSN: | 1477-0520 | ||||||
Official Date: | 23 February 2022 | ||||||
Dates: |
|
||||||
Volume: | 20 | ||||||
Number: | 11 | ||||||
Page Range: | 2194-2199 | ||||||
DOI: | 10.1039/d2ob00196a | ||||||
Status: | Peer Reviewed | ||||||
Publication Status: | Published | ||||||
Access rights to Published version: | Restricted or Subscription Access |
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |