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Cardiovascular risk factors and clinical outcomes of patients hospitalized with COVID-19 pneumonia in Somalia
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Ahmed, Mohammed A. M., Hussein, Ahmed Mohamud, Abdullahi, Aweis Ahmed Moalim, Ahmed, Abdirizak Yusuf, Hussain, Hamdi M. A., Ali, Abdiaziz Mohamed, Barre, Abdulqadir Abdinur, Yusuf, Farhia Mohamud, Olum, Ronald, Sereke, Senai Goitom, Elfadul, Maisa Ahmed, Colebunders, Robert and Bongomin, Felix (2022) Cardiovascular risk factors and clinical outcomes of patients hospitalized with COVID-19 pneumonia in Somalia. Therapeutic Advances in Infectious Disease, 9 . doi:10.1177/20499361221095731 ISSN 2049-9361.
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WRAP-Cardiovascular-risk-factors-and-clinical-outcomes-of-patients-hospitalized-with-COVID-19-pneumonia-in-Somalia-Hussain-2022.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons: Attribution-Noncommercial 4.0. Download (746Kb) | Preview |
Official URL: https://doi.org/10.1177/20499361221095731
Abstract
Background:
Coronavirus disease-2019 (COVID-19) is a potentially life-threatening illness with no established treatment. Cardiovascular risk factors (CRFs) exacerbate COVID-19 morbidity and mortality.
Objective:
To determine the prevalence of CRF and clinical outcomes of patients hospitalized with COVID-19 in a tertiary hospital in Somalia.
Methods:
We reviewed the medical records of patients aged 18 years or older with a real-time polymerase chain reaction (RT-PCR)–confirmed COVID-19 hospitalized at the De Martino Hospital in Mogadishu, Somalia, between March and July 2020.
Results:
We enrolled 230 participants; 159 (69.1%) males, median age was 56 (41–66) years. In-hospital mortality was 19.6% (n = 45); 77.8% in the intensive care unit (ICU) compared with 22.2%, in the general wards (p < 0.001). Age ⩾ 40 years [odds ratio (OR): 3.6, 95% confidence interval (CI): 1.2–10.6, p = 0.020], chronic heart disease (OR: 9.3, 95% CI: 2.2–38.9, p = 0.002), and diabetes mellitus (OR: 3.2, 95% CI: 1.6–6.2, p < 0.001) were associated with increased odds of mortality. Forty-three (18.7%) participants required ICU admission. Age ⩾ 40 years (OR: 7.5, 95% CI: 1.7–32.1, p = 0.007), diabetes mellitus (OR: 3.2, 95% CI: 1.6–6.3, p < 0.001), and hypertension (OR: 2.5, 95% CI: 1.2–5.2, p = 0.014) were associated with ICU admission. For every additional CRF, the odds of admission into the ICU increased threefold (OR: 2.7, 95% CI: 1.2–5.2, p < 0.001), while the odds of dying increased twofold (OR: 2.1, 95% CI: 1.3–3.2, p < 0.001).
Conclusions:
We report a very high prevalence of CRF among patients hospitalized with COVID-19 in Somalia. Mortality rates were unacceptably high, particularly among those with advanced age, underlying chronic heart disease, and diabetes.
| Item Type: | Journal Article | ||||||||
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| Subjects: | R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine R Medicine > RC Internal medicine |
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| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | ||||||||
| Library of Congress Subject Headings (LCSH): | COVID-19 (Disease) -- Risk factors -- Somalia, COVID-19 (Disease) -- Somalia, Cardiovascular system -- Diseases -- Risk factors -- Somalia | ||||||||
| Journal or Publication Title: | Therapeutic Advances in Infectious Disease | ||||||||
| Publisher: | Sage Publications Ltd. | ||||||||
| ISSN: | 2049-9361 | ||||||||
| Official Date: | 25 April 2022 | ||||||||
| Dates: |
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| Volume: | 9 | ||||||||
| Number of Pages: | 9 | ||||||||
| DOI: | 10.1177/20499361221095731 | ||||||||
| Status: | Peer Reviewed | ||||||||
| Publication Status: | Published | ||||||||
| Access rights to Published version: | Open Access (Creative Commons) | ||||||||
| Date of first compliant deposit: | 23 May 2022 | ||||||||
| Date of first compliant Open Access: | 24 May 2022 |
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