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Single-Molecule FRET : methods and biological applications
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Hwang, Ling Chin, Hohlbein, Johannes, Holden, Séamus and Kapanidis, Achillefs N. (2009) Single-Molecule FRET : methods and biological applications. In: Hinterdorfer, P. and Oijen, A., (eds.) Handbook of Single-Molecule Biophysics. New York, NY: Springer, pp. 129-163. ISBN 9780387764962
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Official URL: http://dx.doi.org/10.1007/978-0-387-76497-9_5
Abstract
Since the first single-molecule fluorescence resonance energy transfer (FRET) measurement in 1996, the technique has contributed substantially to our understanding of biological molecules and processes by probing the structure and dynamics of nucleic acids, protein molecules, and their complexes with other molecules. This review discusses basic concepts and current developments in single-molecule FRET methodology, as well as examples of applications to systems such as nucleic acid machines and molecular motors.
Item Type: | Book Item | ||||
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Divisions: | Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) | ||||
Publisher: | Springer | ||||
Place of Publication: | New York, NY | ||||
ISBN: | 9780387764962 | ||||
Book Title: | Handbook of Single-Molecule Biophysics | ||||
Editor: | Hinterdorfer, P. and Oijen, A. | ||||
Official Date: | 25 May 2009 | ||||
Dates: |
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Page Range: | pp. 129-163 | ||||
DOI: | 10.1007/978-0-387-76497-9_5 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published |
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