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Cost-utility analysis of cast compared to removable brace in the management of adult patients with ankle fractures
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Nwankwo, Henry, Mason, James, Costa, Matthew L., Parsons, Nicholas R., Redmond, Anthony, Parsons, Helen, Haque, Aminul and Kearney, Rebecca S. (2022) Cost-utility analysis of cast compared to removable brace in the management of adult patients with ankle fractures. Bone & Joint Open, 3 (6). pp. 455-462. doi:10.1302/2633-1462.36.bjo-2022-0036 ISSN 2633-1462.
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WRAP-cost-utility-analysis-cast-compared-removable-brace-management-adult-patients-with-ankle-fractures-2022.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution Non-commercial No Derivatives 4.0. Download (400Kb) | Preview |
Official URL: https://doi.org/10.1302/2633-1462.36.bjo-2022-0036
Abstract
Aims: To compare the cost-utility of removable brace compared with cast in the management of adult patients with ankle fracture.
Methods: A within-trial economic evaluation conducted from the UK NHS and personnel social services (PSS) perspective. Health resources and quality-of-life data were collected as part of the Ankle Injury Rehabilitation (AIR) multicentre, randomized controlled trial over a 12-month period using trial case report forms and patient-completed questionnaires. Cost-utility analysis was estimated in terms of the incremental cost per quality adjusted life year (QALY) gained. Estimate uncertainty was explored by bootstrapping, visualized on the incremental cost-effectiveness ratio plane. Net monetary benefit and probability of cost-effectiveness were evaluated at a range of willingness-to-pay thresholds and visualized graphically.
Results: The incremental cost and QALYs of using brace over a 12-month period were £46.73 (95% confidence interval (CI) £-9 to £147) and 0.0141 (95% CI -0.005 to 0.033), respectively. The cost per QALY gained was £3,318. The probability of brace being cost-effective at a £30,000 per QALY willingness-to-pay threshold was 88%. The results remained robust to a range of sensitivity analyses.
Conclusion: This within-trial economic evaluation found that it is probable that using a removable brace provides good value to the NHS when compared to cast, in the management of adults with ankle fracture. Cite this article: Bone Jt Open 2022;3(6):455–462.
Item Type: | Journal Article | ||||||
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Subjects: | R Medicine > RD Surgery | ||||||
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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SWORD Depositor: | Library Publications Router | ||||||
Library of Congress Subject Headings (LCSH): | Orthopedics -- Cost effectiveness, Ankle -- Fractures -- Cost effectiveness, Ankle -- Wounds and injuries, Fractures | ||||||
Journal or Publication Title: | Bone & Joint Open | ||||||
Publisher: | British Editorial Society of Bone and Joint Surgery | ||||||
ISSN: | 2633-1462 | ||||||
Official Date: | 1 June 2022 | ||||||
Dates: |
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Volume: | 3 | ||||||
Number: | 6 | ||||||
Page Range: | pp. 455-462 | ||||||
DOI: | 10.1302/2633-1462.36.bjo-2022-0036 | ||||||
Status: | Peer Reviewed | ||||||
Publication Status: | Published | ||||||
Access rights to Published version: | Open Access (Creative Commons) | ||||||
Date of first compliant deposit: | 1 July 2022 | ||||||
Date of first compliant Open Access: | 1 July 2022 | ||||||
RIOXX Funder/Project Grant: |
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