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Prevalence of anxiety symptomatology and diagnosis in syndromic intellectual disability : a systematic review and meta-analysis
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Edwards, Georgina, Jones, Chris, Pearson, Effie, Royston, Rachel, Oliver, Chris, Tarver, Joanne, Crawford, Hayley, Shelley, Lauren and Waite, Jane (2022) Prevalence of anxiety symptomatology and diagnosis in syndromic intellectual disability : a systematic review and meta-analysis. Neuroscience & Biobehavioral Reviews, 138 . 104719. doi:10.1016/j.neubiorev.2022.104719 ISSN 1873-7528.
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WRAP-prevalence-anxiety-symptomatology-diagnosis-syndromic-intellectual-disability-systematic-review-meta-analysis-Crawford-2022.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution 4.0. Download (3564Kb) | Preview |
Official URL: https://doi.org/10.1016/j.neubiorev.2022.104719
Abstract
Individuals with syndromic intellectual disability are at increased risk of experiencing anxiety. Comparing prevalence estimates of anxiety will allow the identification of at-risk groups and inform causal pathways of anxiety. No known study has explored estimates of anxiety symptomatology and diagnosis, including specific anxiety profiles, across groups whilst accounting for methodological quality of studies. This systematic review and meta-analysis aimed to fill this gap. Prior to review completion, methodology and analysis plans were registered and documented in a protocol (CRD42019123561). Data from 83 papers, involving a pooled sample of 13,708 across eight syndromes were synthesised using a random effects model. Anxiety prevalence ranged from 9 % (95 % CI: 4-14) in Down syndrome to 73% in Rett syndrome (95 % CI: 70-77). Anxiety prevalence across syndromic intellectual disability was higher than for intellectual disability of mixed aetiology and general population estimates. Substantial variability between syndromes identified groups at higher risk than others. The identification of high-risk groups is crucial for early intervention, allowing us to refine models of risk and identify divergent profiles.
Item Type: | Journal Article | |||||||||
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Subjects: | B Philosophy. Psychology. Religion > BF Psychology R Medicine > RC Internal medicine |
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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SWORD Depositor: | Library Publications Router | |||||||||
Library of Congress Subject Headings (LCSH): | Anxiety , Intellectual disability , People with mental disabilities -- Care | |||||||||
Journal or Publication Title: | Neuroscience & Biobehavioral Reviews | |||||||||
Publisher: | Elsevier | |||||||||
ISSN: | 1873-7528 | |||||||||
Official Date: | July 2022 | |||||||||
Dates: |
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Volume: | 138 | |||||||||
Article Number: | 104719 | |||||||||
DOI: | 10.1016/j.neubiorev.2022.104719 | |||||||||
Status: | Peer Reviewed | |||||||||
Publication Status: | Published | |||||||||
Access rights to Published version: | Open Access (Creative Commons) | |||||||||
Date of first compliant deposit: | 7 September 2022 | |||||||||
Date of first compliant Open Access: | 12 September 2022 | |||||||||
RIOXX Funder/Project Grant: |
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